AC T09033
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ID T09033
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DT 08.06.2006 (created); jag.
DT 16.09.2014 (updated); hna.
CO Copyright (C), QIAGEN.
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FA TEF-1
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SY GT-IIC; MCBF; Sph factor; TEF1; transcriptional enhancer factor 1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004668 TEAD1; HGNC: TEAD1.
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CL C0024; TEA.
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SZ 426 AA; 47.9 kDa (cDNA) (calc.), 53 kDa (SDS) [2] [2]
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SQ MEPSSWSGSESPAENMERMSDSADKPIDNDAEGVWSPDIEQSFQEALAIYPPCGRRKIIL
SQ SDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSRDFHSKLKDQTAKDKALQ
SQ HMAAMSSAQIVSATAIHNKLGLPGIPRPTFPGAPGFWPGMIQTGQPGSSQDVKPFVQQAY
SQ PIQPAVTAPIPGFEPASAPAPSVPAWQGRSIGTTKLRLVEFSAFLEQQRDPDSYNKHLFV
SQ HIGHANHSYSDPLLESVDIRQIYDKFPEKKGGLKELFGKGPQNAFFLVKFWADLNCNIQD
SQ DAGAFYGVTSQYESSENMTVTCSTKVCSFGKQVVEKVETEYARFENGRFVYRINRSPMCE
SQ YMINFIHKLKHLPEKYMMNSVLENFTILLVVTNRDTQETLLCMACVFEVSNSEHGAQHHI
SQ YRLVKD
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SC Swiss-Prot#P28347
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FT 2 418 
PF01285; TEA/ATTS domain family.
FT 26 97 
SM00426; TEA.
FT 30 97 
PS51088; TEA_2.
FT 65 420 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 167 426 
trans-activating region [3].
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IN T01567 Max-isoform1; human, Homo sapiens.
IN T25795 TAZ-isoform1; mouse, Mus musculus.
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MX M00704 V$TEF1_Q6.
MX M01817 V$TEF1_Q6_03.
MX M07340 V$TEF1_Q6_04.
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BS R31422.
BS R31423.
BS R31424.
BS R31425.
BS R31426.
BS R29458.
BS R31389.
BS R21285.
BS R21550.
BS R63964.
BS R21291.
BS R21292.
BS R21296.
BS R26432.
BS R09232.
BS R21290.
BS R26314.
BS R01403.
BS R01417.
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DR TRANSPATH: MO000082679.
DR UniProtKB: P28347;
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RN [1]; RE0000071.
RX PUBMED: 2986843.
RA Emerson B. M., Lewis C. D., Felsenfeld G.
RT Interaction of specific nuclear factors with the nuclease-hypersensitive region of the chicken adult beta-globin gene: nature of the binding domain
RL Cell 41:21-30 (1985).
RN [2]; RE0000125.
RX PUBMED: 2843293.
RA Davidson I., Xiao J. H., Rosales R., Staub A., Chambon P.
RT The HeLa cell protein TEF-1 binds specifically and cooperatively to two SV40 enhancer motifs of unrelated sequence
RL Cell 54:931-942 (1988).
RN [3]; RE0000183.
RX PUBMED: 1851669.
RA Xiao J. H., Davidson I., Matthes H., Garnier J.-M., Chambon P.
RT Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1
RL Cell 65:551-568 (1991).
RN [4]; RE0000256.
RX PUBMED: 2070413.
RA Buerglin T. R.
RT The TEA domain: a novel, highly conserved DNA-binding motif
RL Cell 66:11-12 (1991).
RN [5]; RE0000368.
RX PUBMED: 2826126.
RA Xiao J. H., Davidson I., Ferrandon D., Rosales R., Vigneron M., Macchi M., Ruffenach F., Chambon P.
RT One cell-specific and three ubiquitous proteins bind in vitro to overlapping motifs in the domain B1 of the SV40 enhancer
RL EMBO J. 6:3005-3013 (1987).
RN [6]; RE0000404.
RX PUBMED: 2548845.
RA Mercurio F., Karin M.
RT Transcription factors AP-3 and AP-2 interact with the SV40 enhancer in a mutually exclusive manner
RL EMBO J. 8:1455-1460 (1989).
RN [7]; RE0001261.
RX PUBMED: 3600658.
RA Kemper B., Jackson P. D., Felsenfeld G.
RT Protein-Binding Sites within the 5' DNase I-Hypersensitive Region of the Chicken alphaD-Globin Gene
RL Mol. Cell. Biol. 7:2059-2069 (1987).
RN [8]; RE0005291.
RX PUBMED: 8389695.
RA Hwang J.-J., Chambon P., Davidson I.
RT Characterization of the transcription activation function and the DNA binding domain of transcriptional enhancer factor-1
RL EMBO J. 12:2337-2348 (1993).
RN [9]; RE0005292.
RX PUBMED: 7958896.
RA Chen Z., Friedrich G. A., Soriano P.
RT Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice
RL Genes Dev. 8:2293-2301 (1994).
RN [10]; RE0005293.
RX PUBMED: 8035807.
RA Chaudhary S., Brou C., Valentin M.-E., Burton N., Tora L., Chambon P., Davidson I.
RT A cell-specific factor represses stimulation of transcription in vitro by transcriptional enhancer factor 1
RL Mol. Cell. Biol. 14:5290-5299 (1994).
RN [11]; RE0005294.
RX PUBMED: 8441689.
RA Blatt C., DePamphilis M. L.
RT Striking homology between the mouse and human transcriptional enhancer factor-1 (TEF-1)
RL Nucleic Acids Res. 21:747-748 (1993).
RN [12]; RE0005295.
RX PUBMED: 8106348.
RA Stewart A. F., Larkin S. B., Farrance I. K., Mar J. H., Hall D. E., Ordahl C. P.
RT Muscle-enriched TEF-1 isoforms bind M-CAT elements from muscle-specific promoters and differentially activate transcription
RL J. Biol. Chem. 269:3147-3150 (1994).
RN [13]; RE0047848.
RX PUBMED: 10931933.
RA Gupta M. P., Kogut P., Gupta M.
RT Protein kinase-A dependent phosphorylation of transcription enhancer factor-1 represses its DNA-binding activity but enhances its gene activation ability.
RL Nucleic Acids Res. 28:3168-3177 (2000).
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