AC T09217
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ID T09217
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DT 11.08.2006 (created); sou.
DT 03.07.2015 (updated); jmh.
CO Copyright (C), QIAGEN.
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FA MafB
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SY (SEGMENTATION protein KR) (KREISLER); Kr; kreisler; KRML; MAF1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G009014 Mafb.
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CL C0008; bZIP.
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SZ 323 AA; 35.8 kDa (gene) (calc.).
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SQ MAAELSMGQELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTPL
SQ STPCSSVPSSPSFSPTEPKTHLEDLYWMASNYQQMNPEALNLTPEDAVEALIGSHPVPQP
SQ LQSFDGFRSAHHHHHHHHPHPHHGYPGAGVTHDDLGQHAHPHHHHHHQASPPPSSAASPA
SQ QQLPTSHPGPGPHATAAATAAGGNGSVEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLK
SQ QKRRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEK
SQ LANSGFREAGSTSDSPSSPEFFL
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SC translated from EMBL #L36434
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FT 209 303 
PF03131; bZIP Maf transcription factor.
FT 234 300 
SM00338; brlzneu.
FT 238 301 
PS50217; BZIP.
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CP MafB is expressed in Alpha cells but not in Beta and Delta cells in the adult pancreas. MafB was found in glucagon+ and insulin+ cells by E10.5 and E12.5.In contrast to the pancreas, MafB was expressed in essentially all pdx1+ cells along the villi of the duodenum at P4 and at lower levels in many Pdx1+ cells in the duodenal crypts. MafB expression is maintained in insulin- and glucagon- producing cells of ax4- and Pax6- deficient animals [3].
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IN T17679 c-Myb; Mammalia.
IN T00681 Pax-6; mouse, Mus musculus.
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MX M01227 V$MAFB_01.
MX M02879 V$MAFB_03.
MX M02775 V$MAFB_05.
MX M03830 V$MAFB_Q4.
MX M08888 V$MAFB_Q4_01.
MX M07296 V$MAF_Q4.
MX M00983 V$MAF_Q6_01.
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BS R68625.
BS R68626.
BS R65780.
BS R20841.
BS R20765.
BS R20779.
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DR TRANSPATH: MO000084924.
DR EMBL: L36434; MMBDLZ.
DR EMBL: L36435;
DR UniProtKB: P54841;
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RN [1]; RE0004642.
RX PUBMED: 8001130.
RA Cordes S. P., Barsh G. S.
RT The mouse segmentation gene kr encods a novel basic domain-leucine zipper transcription factor
RL Cell 79:1025-1034 (1994).
RN [2]; RE0048003.
RX PUBMED: 9566892.
RA Hedge S. P., Kumar A., Kurschner C., Shapiro L. H.
RT c-Maf interacts with c-Myb to regulate transcription of an early myeloid gene during differentiation.
RL Mol. Cell. Biol. 18:2729-2737 (1998).
RN [3]; RE0049660.
RX PUBMED: 16443760.
RA Artner I., Le Lay J., Hang Y., Elghazi L., Schisler J. C., Henderson E., Sosa-Pineda B., Stein R.
RT MafB: an activator of the glucagon gene expressed in developing islet alpha- and beta-cells.
RL Diabetes 55:297-304 (2006).
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