AC T09236
XX
ID T09236
XX
DT 16.08.2006 (created); din.
DT 10.06.2015 (updated); jmh.
CO Copyright (C), QIAGEN.
XX
FA Cdx-2
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SY caudal homolog homeobox protein 2; caudal type homeo box 2; Cdx-2; CDX2.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G001230 Cdx2.
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CL C0006; homeo.
XX
SZ 311 AA; 33.5 kDa (gene) (calc.), 37 kDa (SDS) [3]
XX
SQ MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAATANLDSAQS
SQ PGPSWPTAYGAPLREDWNGYAPGGAAAANAVAHGLNGGSPAAAMGYSSPAEYHAHHHPHH
SQ HPHHPAASPSCASGLLQTLNLGPPGPAATAAAEQLSPSGQRRNLCEWMRKPAQQSLGSQV
SQ KTRTKDKYRVVYTDHQRLELEKEFHFSRYITIRRKSELAATLGLSERQVKIWFQNRRAKE
SQ RKIKKKQQQQQQQQQQQPPQPPPQPSQPQPGALRSVPEPLSPVTSLQGSVPGSVPGVLGP
SQ AGGVLNSTVTQ
XX
SC Swiss-Prot#P43241
XX
FT 13 179 
PF04731; Caudal like protein activation region.
FT 15 180 
activation domain [6].
FT 183 243 
PS50071; HOMEOBOX_2.
FT 185 247 
SM00389; HOX_1.
FT 186 242 
PF00046; Homeobox domain.
XX
IN T00759 Sp1; human, Homo sapiens.
XX
MX M01449 V$CDX2_01.
MX M00729 V$CDX2_Q5.
MX M01659 V$CDX2_Q5_01.
MX M02087 V$CDX2_Q5_02.
MX M07416 V$CDX2_Q6.
MX M07378 V$CDX_Q4.
MX M00991 V$CDX_Q5.
XX
BS R26172.
BS R14712.
BS R28996.
BS R28997.
BS R28998.
BS R28999.
BS R29000.
BS R04239.
BS R41285.
BS R08858.
BS R08859.
BS R68202.
BS R68204.
BS R68205.
BS R68207.
BS R68209.
BS R68210.
BS R08873.
XX
DR TRANSPATH: MO000085124.
DR TRANSCOMPEL: C00583.
DR EMBL: U00454;
DR UniProtKB: P43241;
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RN [1]; RE0005015.
RX PUBMED: 1671571.
RA James R. J., Kazenwadel J.
RT Homeobox gene expression in the intetnal epithelium of adult mice
RL J. Biol. Chem. 266:3246-3251 (1991).
RN [2]; RE0005016.
RX PUBMED: 7910823.
RA James R. J., Erler T., Kazenwadel J.
RT Structure of the murine homeobox gene cdx-2. Expression in embryonic and adult intestine epithelium
RL J. Biol. Chem. 269:15229-15237 (1994).
RN [3]; RE0005017.
RX PUBMED: 7935448.
RA Suh E., Chen L., Taylor J., Traber P. G.
RT A homeodomain protein related to caudal regulates intestine-specific gene transcription
RL Mol. Cell. Biol. 14:7340-7351 (1994).
RN [4]; RE0011831.
RX PUBMED: 8524295.
RA Jin T., Drucker D. J.
RT Activation of proglucagon gene transcription through a novel promoter element by the caudal-related homeodomain protein cdx-2/3
RL Mol. Cell. Biol. 16:19-28 (1996).
RN [5]; RE0014381.
RX PUBMED: 8552090.
RA Suh E., Traber P. G.
RT An intestine-specific homeobox gene regulates proliferation and differentiation
RL Mol. Cell. Biol. 16:619-625 (1996).
RN [6]; RE0014389.
RX PUBMED: 9171078.
RA Taylor J. K., Levy T., Suh E. R., Traber P. G.
RT Activation of enhancer elements by the homeobox gene Cdx2 is cell line specific
RL Nucleic Acids Res. 25:2293-2300 (1997).
RN [7]; RE0014407.
RX PUBMED: 9428790.
RA Taylor J. K., Boll W., Levy T., Suh E., Siang S., Mantei N., Traber P. G.
RT Comparison of intestinal phospholipase A/lysophospholipase and sucrase-isomaltase genes suggest a common structure for enterocyte-specific promoters
RL DNA Cell Biol. 16:1419-1428 (1997).
RN [8]; RE0052368.
RX PUBMED: 16616718.
RA Shimakura J., Terada T., Shimada Y., Katsura T., Inui K.
RT The transcription factor Cdx2 regulates the intestine-specific expression of human peptide transporter 1 through functional interaction with Sp1.
RL Biochem. Pharmacol. 71:1581-1588 (2006).
XX
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