AC T09294
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ID T09294
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DT 04.09.2006 (created); ili.
DT 12.05.2014 (updated); sup.
CO Copyright (C), QIAGEN.
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FA C/EBPbeta-LAP
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SY C/EBP-beta; C/EBP-beta2; CCAAT/enhancer binding protein (C/EBP), beta; CEBPB; CRP2; IL6DBP; LAP; MGC32080; NF-IL6; NF-IL6-2; TCF5.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002899 CEBPB; HGNC: CEBPB.
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CL C0008; bZIP.
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SZ 322 AA; 33.6 kDa (cDNA) (calc.).
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SQ MEVANFYYEADCLAAAYGGKAAPAAPPAARPGPRPPAGELGSIGDHERAIDFSPYLEPLG
SQ APQAPAPATATDTFEAAPPAPAPAPASSGQHHDFLSDLFSDDYGGKNCKKPAEYGYVSLG
SQ RLGAAKGALHPGCFAPLHPPPPPPPPPAELKAEPGFEPADCKRKEEAGAPGGGAGMAAGF
SQ PYALRAYLGYQAVPSGSSGSLSTSSSSSPPGTPSPADAKAPPTACYAGAAPAPSQVKSKA
SQ KKTVDKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRE
SQ LSTLRNLFKQLPEPLLASSGHC
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SC Swiss-Prot#P17676, edited
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FT 246 310 SM00338; brlzneu.
FT 247 300 PF07716; bZIP_2.
FT 248 311 PS50217; BZIP.
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SF one of three forms encoded by the human CEBPbeta gene that result from the usage of different in frame AUGs of the same mRNA species;
SF C/EBPbeta-LAP isoform results from the usage of an alternative initiation site at position 24 of the protein sequence of the NF-IL6-1 isoform;
SF is identical to the C-terminal 322 AA of the NF-IL6-1 isoform [1];
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IN T05499 BAF47; human, Homo sapiens.
IN T05451 BRG1; human, Homo sapiens.
IN T01261 Brm; human, Homo sapiens.
IN T22463 SNF2H; human, Homo sapiens.
IN T22464 SNF2H; human, Homo sapiens.
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MX M00109 V$CEBPB_01.
MX M00117 V$CEBPB_02.
MX M07315 V$CEBPB_Q3.
MX M01896 V$CEBPB_Q6.
MX M00912 V$CEBP_Q2_01.
MX M00770 V$CEBP_Q3.
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BS R57760.
BS R57763.
BS R57764.
BS R57852.
BS R61705.
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DR TRANSPATH: MO000086278.
DR UniProtKB: P17676-2;
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RN [1]; RE0004730.
RX PUBMED: 8264594.
RA Hsu W., Kerppola T. K., Chen P.-L., Curran T., Chen-Kiang S.
RT Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region
RL Mol. Cell. Biol. 14:268-276 (1994).
RN [2]; RE0068544.
RX PUBMED: 18820298.
RA Wang W. L., Lee Y. C., Yang W. M., Chang W. C., Wang J. M.
RT Sumoylation of LAP1 is involved in the HDAC4-mediated repression of COX-2 transcription.
RL Nucleic Acids Res. 36:6066-6079 (2008).
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