AC T01261
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ID T01261
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DT 18.10.1994 (created); ewi.
DT 17.08.2012 (updated); din.
CO Copyright (C), QIAGEN.
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FA Brm
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SY BAF190; brahma; hbrm; hSNF2a; SMARCA2; SNF2-alpha; SNF2-like 2; SNF2/SWI2-like protein 2; SNF2L2; SNF2LA; Sth1p; sucrose nonfermenting 2-like protein 2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G005169 SMARCA2; HGNC: SMARCA2.
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HO brm (Drosophila), SNF2/SWI2 (yeast).
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SF C-terminal end: bromodomain;
SF 7 domains with homology to helicases;
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FF activator, may co-operate with GR;
FF putative helicase;
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IN T18770 ARID1B; human, Homo sapiens.
IN T05452 BAF155; human, Homo sapiens.
IN T22426 BAF170; human, Homo sapiens.
IN T18766 BAF250; human, Homo sapiens.
IN T05499 BAF47; human, Homo sapiens.
IN T06126 BAF53a; human, Homo sapiens.
IN T22424 BAF57; human, Homo sapiens.
IN T05453 BAF60A; human, Homo sapiens.
IN T22468 BCL11A-isoform1; human, Homo sapiens.
IN T05451 BRG1; human, Homo sapiens.
IN T00105 C/EBPalpha; human, Homo sapiens.
IN T00459 C/EBPbeta-FL; rat, Rattus norvegicus.
IN T06595 C/EBPbeta-FL; human, Homo sapiens.
IN T02105 C/EBPbeta-LAP; rat, Rattus norvegicus.
IN T09294 C/EBPbeta-LAP; human, Homo sapiens.
IN T06596 C/EBPbeta-LIP; human, Homo sapiens.
IN T08505 COUP-TF1; human, Homo sapiens.
IN T22508 dpf2-isoform1; human, Homo sapiens.
IN T00261 ER-alpha; human, Homo sapiens.
IN T04687 NCOR1; human, Homo sapiens.
IN T14940 NF-kappaB2; human, Homo sapiens.
IN T01931 RelB; human, Homo sapiens.
IN T14622 sin3a; human, Homo sapiens.
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BS R29083.
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DR TRANSPATH: MO000025538.
DR UniProtKB: P51531;
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RN [1]; RE0000547.
RX PUBMED: 8223438.
RA Muchardt C., Yaniv M.
RT A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor
RL EMBO J. 12:4279-4290 (1993).
RN [2]; RE0036149.
RX PUBMED: 9099865.
RA Ichinose H., Garnier J. M., Chambon P., Losson R.
RT Ligand-dependent interaction between the estrogen receptor and the human homologues of SWI2/SNF2.
RL Gene 188:95-100 (1997).
RN [3]; RE0047084.
RX PUBMED: 15170388.
RA Wang X., Nagl N. G., Wilsker D., Van Scoy M., Pacchione S., Yaciuk P., Dallas P. B., Moran E.
RT Two related ARID family proteins are alternative subunits of human SWI/SNF complexes
RL Biochem. J. 383:319-25 (2004).
RN [4]; RE0048907.
RX PUBMED: 12200431.
RA Inoue H., Furukawa T., Giannakopoulos S., Zhou S., King D. S., Tanese N.
RT Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors.
RL J. Biol. Chem. 277:41674-41685 (2002).
RN [5]; RE0055471.
RX PUBMED: 19054766.
RA Dhawan P., Weider R., Christakos S.
RT CCAAT Enhancer-binding Protein {alpha} Is a Molecular Target of 1,25-Dihydroxyvitamin D3 in MCF-7 Breast Cancer Cells.
RL J. Biol. Chem. 284:3086-3095 (2009).
RN [6]; RE0065412.
RX PUBMED: 19525936.
RA Peng G., Yim E. K., Dai H., Jackson A. P., Burgt I., Pan M. R., Hu R., Li K., Lin S. Y.
RT BRIT1/MCPH1 links chromatin remodelling to DNA damage response.
RL Nat. Cell Biol. 11:865-872 (2009).
RN [7]; RE0070954.
RX PUBMED: 20460684.
RA Tando T., Ishizaka A., Watanabe H., Ito T., Iida S., Haraguchi T., Mizutani T., Izumi T., Isobe T., Akiyama T., Inoue J., Iba H.
RT Requiem protein links RelB/p52 and the Brm-type SWI/SNF complex in a noncanonical NF-kappaB pathway.
RL J. Biol. Chem. 285:21951-21960 (2010).
RN [8]; RE0074383.
RX PUBMED: 19112178.
RA Zhang L. J., Liu X., Gafken P. R., Kioussi C., Leid M.
RT A chicken ovalbumin upstream promoter transcription factor I (COUP-TFI) complex represses expression of the gene encoding tumor necrosis factor alpha-induced protein 8 (TNFAIP8).
RL J. Biol. Chem. 284:6156-6168 (2009).
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