
AC   T02105
XX
ID   T02105
XX
DT   03.03.1997 (created); ewi.
DT   24.04.2015 (updated); sup.
CO   Copyright (C), QIAGEN.
XX
FA   C/EBPbeta-LAP
XX
SY   C/EBPbeta(p34); C/EBPbeta2; CCAAT/enhancer binding protein (C/EBP), beta; CEBPB; IL6DBP; LAP; NF-IL6; p34(C/EBPbeta); TCF5.
XX
OS   rat, Rattus norvegicus
OC   eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE   G013627 Cebpb.
XX
CL   C0008; bZIP.
XX
SZ   276 AA; 29.2 kDa (cDNA) (calc.), 34 kDa (SDS) [1]
XX
SQ   MEVANFYYEPDCLAYGAKAARAAPRAPAAEPAIGEHERAIDFSPYLEPLAPAAADFAAPA
SQ   PAHHDFLSDLFADDYGAKPSKKPSDYGYVSLGRAGAKAAPPACFPPPPPAALKAEPGFEP
SQ   ADCKRADDAPAMAAGFPFALRAYLGYQATPSGSSGSLSTSSSSSPPGTPSPADAKAAPAA
SQ   CFAGPPAAPAKAKAKKAVDKLSDEYKMRRERNNIAVRKSRDKAKMRNLETQHKVLELTAE
SQ   NERLQKKVEQLSRELSTLRNLFKQLPEPLLASAGHC
XX
SC   edited Swiss-Prot #P21272
XX
FT        1     10    activation domain module 1 (ADM1) [2].
FT       33     51
   activation domain module 1 (ADM1) [2].
FT       33     51    activation domain module 2 (ADM2) [2].
FT       63     72
   activation domain module 2 (ADM2) [2].
FT       63     72    activation domain module 3 (ADM3) [2].
FT      116    149
   activation domain module 3 (ADM3) [2].
FT      116    149    regulatory domain 1 (RD1) [2].
FT      163    191
   regulatory domain 1 (RD1) [2].
FT      163    191    regulatory domain 2 (RD2) [2].
FT      200    264
   regulatory domain 2 (RD2) [2].
FT      200    264    SM00338; brlzneu.
FT      201    254
   SM00338; brlzneu.
FT      201    254    PF07716; Basic region leucine zipper.
FT      202    265
   PF07716; Basic region leucine zipper.
FT      202    265    PS50217; BZIP.
   PS50217; BZIP.
 XX
SF   alternative translation initiation product to C/EBPbeta [1];
SF   RD1 is a powerful inhibitory domain [2];
SF   RD2 represses DNA-binding specifically in fibroblast-like cells (L cell line) [2];
XX
FF   activating and repressing properties [1] [2];
XX
IN   T05452 BAF155; human, Homo sapiens.
IN   T05499 BAF47; human, Homo sapiens.
IN   T05451 BRG1; human, Homo sapiens.
IN   T01261 Brm; human, Homo sapiens.
IN   T00459 C/EBPbeta-FL; rat, Rattus norvegicus.
IN   T01420 C/EBPbeta-LIP; rat, Rattus norvegicus.
XX
MX   M00109 V$CEBPB_01.
MX   M00117 V$CEBPB_02.
MX   M07315 V$CEBPB_Q3.
MX   M01896 V$CEBPB_Q6.
MX   M00912 V$CEBP_Q2_01.
MX   M00770 V$CEBP_Q3.
XX
BS   R60572.
BS   R60573.
BS   R59480.
BS   R58214.
BS   R58215.
BS   R58216.
BS   R58217.
BS   R58218.
BS   R58222.
BS   R58225.
BS   R58226.
BS   R58227.
BS   R58228.
BS   R58229.
BS   R58230.
BS   R58231.
BS   R58237.
BS   R63552.
BS   R34472.
BS   R67365.
BS   R01344.
XX
DR   TRANSPATH: MO000026168.
DR   UniProtKB: P21272-2;
XX
RN   [1]; RE0002865.
RX   PUBMED: 1934061.
RA   Descombes P., Schibler U.
RT   A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA
RL   Cell 67:569-579 (1991).
RN   [2]; RE0003538.
RX   PUBMED: 7621830.
RA   Williams S. C., Baer M., Dillner A. J., Johnson P. F.
RT   CRP2 (C/EBPbeta) contains a bipartite regulatory domain that controls transcriptional activation, DNA binding and cell specificity
RL   EMBO J. 14:3170-3183 (1995).
RN   [3]; RE0007055.
RX   PUBMED: 8007984.
RA   Sears R. C., Sealy L.
RT   Multiple forms of C/EBP beta bind the EFII enhancer sequence in the Rous sarcoma virus long terminal repeat
RL   Mol. Cell. Biol. 14:4855-4871 (1994).
XX
//
XX
SF   alternative translation initiation product to C/EBPbeta [1];
SF   RD1 is a powerful inhibitory domain [2];
SF   RD2 represses DNA-binding specifically in fibroblast-like cells (L cell line) [2];
XX
FF   activating and repressing properties [1] [2];
XX
IN   T05452 BAF155; human, Homo sapiens.
IN   T05499 BAF47; human, Homo sapiens.
IN   T05451 BRG1; human, Homo sapiens.
IN   T01261 Brm; human, Homo sapiens.
IN   T00459 C/EBPbeta-FL; rat, Rattus norvegicus.
IN   T01420 C/EBPbeta-LIP; rat, Rattus norvegicus.
XX
MX   M00109 V$CEBPB_01.
MX   M00117 V$CEBPB_02.
MX   M07315 V$CEBPB_Q3.
MX   M01896 V$CEBPB_Q6.
MX   M00912 V$CEBP_Q2_01.
MX   M00770 V$CEBP_Q3.
XX
BS   R60572.
BS   R60573.
BS   R59480.
BS   R58214.
BS   R58215.
BS   R58216.
BS   R58217.
BS   R58218.
BS   R58222.
BS   R58225.
BS   R58226.
BS   R58227.
BS   R58228.
BS   R58229.
BS   R58230.
BS   R58231.
BS   R58237.
BS   R63552.
BS   R34472.
BS   R67365.
BS   R01344.
XX
DR   TRANSPATH: MO000026168.
DR   UniProtKB: P21272-2;
XX
RN   [1]; RE0002865.
RX   PUBMED: 1934061.
RA   Descombes P., Schibler U.
RT   A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA
RL   Cell 67:569-579 (1991).
RN   [2]; RE0003538.
RX   PUBMED: 7621830.
RA   Williams S. C., Baer M., Dillner A. J., Johnson P. F.
RT   CRP2 (C/EBPbeta) contains a bipartite regulatory domain that controls transcriptional activation, DNA binding and cell specificity
RL   EMBO J. 14:3170-3183 (1995).
RN   [3]; RE0007055.
RX   PUBMED: 8007984.
RA   Sears R. C., Sealy L.
RT   Multiple forms of C/EBP beta bind the EFII enhancer sequence in the Rous sarcoma virus long terminal repeat
RL   Mol. Cell. Biol. 14:4855-4871 (1994).
XX
//