AC T09366
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ID T09366
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DT 06.10.2006 (created); ech.
DT 22.09.2015 (updated); smt.
CO Copyright (C), QIAGEN.
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FA foxl2
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SY BPES; forkhead box L2; FOXL2; PFRK; PINTO; Putative transcription factor foxl2.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G037409 Foxl2.
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CL C0023; fork head.
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SZ 375 AA; 38.9 kDa (gene) (calc.).
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SQ MMASYPEPEDTAGTLLAPESGRAVKEAEASPPSPGKGGGTTPEKPDPAQKPPYSYVALIA
SQ MAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGERK
SQ GNYWTLDPACEDMFEKGNYRRRRRMKRPFRPPPAHFQPGKGLFGSGGAAGGCGVPGAGAD
SQ GYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAAAAAAAAAAAAGPGSPGAAAV
SQ VKGLAGPAASYGPYSRVQSMALPPGVVNSYNGLGGPPAAPPPPPPPPHPHPHPHAHHLHA
SQ AAAPPPAPPHHGAAAPPPGQLSPASPATAAPPAPAPTSAPGLQFACARQPELAMMHCSYW
SQ DHDSKTGALHSRLDL
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SC translated from EMBL:AY094605
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FT 48 138 
SM00339; forkneu4.
FT 50 144 
PS50039; FORK_HEAD_3.
FT 50 145 
PF00250; Fork_head.
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FF is required for pituitary development [1];
FF participate in the regulation of a specific epithelial transport process [4];
FF is required for commitment to ovary differentiation [3];
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IN T00291 FosB; mouse, Mus musculus.
IN T09366 foxl2; mouse, Mus musculus.
IN T10683 Smad2; human, Homo sapiens.
IN T04096 Smad3-isoform1; human, Homo sapiens.
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MX M03548 V$FOXL2_Q2.
MX M08811 V$FOXL2_Q5.
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BS R72487.
BS R72488.
BS R24203.
BS R40111.
BS R70183.
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DR TRANSPATH: MO000088310.
DR TRANSCOMPEL: C00557.
DR TRANSCOMPEL: C00574.
DR EMBL: AY094605;
DR UniProtKB: O88470;
DR UniProtKB: Q2TVT7; Q2TVT7.
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RN [1]; RE0048389.
RX PUBMED: 16840539.
RA Ellsworth B. S., Egashira N., Haller J. L., Butts D. L., Cocquet J., Clay C. M., Osamura R. Y., Camper S. A.
RT FOXL2 in the Pituitary: Molecular, Genetic and Developmental Analysis.
RL Mol. Endocrinol. 20:2796-2805 (2006).
RN [2]; RE0048390.
RX PUBMED: 16647286.
RA Uhlenhaut N. H., Treier M.
RT Foxl2 function in ovarian development.
RL Mol. Genet. Metab. 88:225-234 (2006).
RN [3]; RE0048392.
RX PUBMED: 15944199.
RA Ottolenghi C., Omari S., Garcia-Ortiz J. E., Uda M., Crisponi L., Forabosco A., Pilia G., Schlessinger D.
RT Foxl2 is required for commitment to ovary differentiation.
RL Hum. Mol. Genet. 14:2053-2062 (2005).
RN [4]; RE0048393.
RX PUBMED: 15155178.
RA Katz J. P., Perreault N., Goldstein B. G., Chao H. H., Ferraris R. P., Kaestner K. H.
RT Foxl1 null mice have abnormal intestinal epithelia, postnatal growth retardation, and defective intestinal glucose uptake.
RL Am. J. Physiol. Gastrointest. Liver Physiol. 287:G856-64 (2004).
RN [5]; RE0065639.
RX PUBMED: 19324968.
RA Lamba P., Fortin J., Tran S., Wang Y., Bernard D. J.
RT A novel role for the forkhead transcription factor FOXL2 in activin A-regulated follicle-stimulating hormone beta subunit transcription.
RL Mol. Endocrinol. 23:1001-1013 (2009).
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