AC T09467
XX
ID T09467
XX
DT 12.10.2006 (created); ask.
DT 15.05.2013 (updated); sup.
CO Copyright (C), QIAGEN.
XX
FA SF-1
XX
SY Ad4BP; fushi tarazu factor homolog 1; NR5A1; steroidogenic factor 1.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G004015 NR5A1; HGNC: NR5A1.
XX
CL C0002; CC (rec).
XX
SZ 461 AA; 51.6 kDa (cDNA) (calc.).
XX
SQ MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKT
SQ QRNRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKL
SQ ETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPL
SQ AGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQV
SQ RARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQN
SQ CWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLA
SQ LQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLL
SQ LCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
XX
SC Swiss-Prot#Q13285
XX
FT 10 81 
SM00399; c4gold.
FT 10 85 
PS51030; NUCLEAR_REC_DBD_2.
FT 11 86 
PF00105; Zinc finger, C4 type (two domains).
FT 31 35 
P-box [4].
FT 50 54 
D-box [4].
FT 267 430 
SM00430; holi.
FT 270 455 
PF00104; Ligand-binding domain of nuclear hormon.
XX
IN T08412 beta-catenin; mouse, Mus musculus.
IN T11171 foxl2; human, Homo sapiens.
XX
MX M03802 V$SF1_Q5.
MX M07267 V$SF1_Q5_01.
MX M00727 V$SF1_Q6.
MX M01132 V$SF1_Q6_01.
XX
BS R16935.
BS R41539.
BS R20512.
BS R20628.
BS R20629.
BS R28184.
BS R26485.
BS R28189.
BS R41535.
BS R09693.
BS R09694.
BS R27948.
BS R56046.
BS R28522.
BS R28524.
BS R09636.
BS R29509.
BS R20624.
BS R20644.
BS R12704.
BS R12705.
BS R21181.
BS R12700.
BS R12693.
BS R12701.
BS R12702.
BS R12703.
XX
DR TRANSPATH: MO000089010.
DR EMBL: D88155; HSD155.
DR EMBL: U76388; HSU76388.
DR UniProtKB: Q13285; STF1_HUMAN.
XX
RN [1]; RE0013625.
RX PUBMED: 10219237.
RA Nuclear Receptors Nomenclature Committee.
RT A unified nomenclature system for the nuclear receptor superfamily
RL Cell 97:161-163 (1999).
RN [2]; RE0013658.
RX PUBMED: 8806624.
RA Oba K., Yanase T., Nomura M., Morohashi K., Takayanagi R., Nawata H.
RT Structural characterization of human Ad4bp (SF-1) gene
RL Biochem. Biophys. Res. Commun. 226:261-267 (1996).
RN [3]; RE0015434.
RX PUBMED: 10913126.
RA Ito M., Achermann J. C., Jameson J. L.
RT A naturally occurring steroidogenic factor-1 mutation exhibits differential binding and activation of target genes
RL J. Biol. Chem. 275:31708-31714 (2000).
RN [4]; RE0015435.
RX PUBMED: 10369247.
RA Achermann J. C., Ito M., Ito M., Hindmarsh P. C., Jameson J. L.
RT A mutation in the gene encoding steroidogenic factor-1 causes XY sex reversal and adrenal failure in humans
RL Nat. Genet. 22:125-126 (1999).
RN [5]; RE0015452.
RX PUBMED: 8964846.
RA Asa S. L., Bamberger A. M., Cao B., Wong M., Parker K. L., Ezzat S.
RT The transcription activator steroidogenic factor-1 is preferentially expressed in the human pituitary gonadotroph
RL J. Clin. Endocrinol. Metab. 81:2165-2170 (1996).
XX
//