AC T09540
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ID T09540
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DT 31.10.2006 (created); ask.
DT 27.05.2011 (updated); grs.
CO Copyright (C), QIAGEN.
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FA c-Krox
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SY c-Krox; Krueppel-related zinc finger protein cKrox; MGC102577; T-helper-inducing POZ/Krueppel-like factor; Thpok; ZBTB7B; Zfp-67; ZFP67; Zinc finger and BTB domain containing 7B; Zinc finger and BTB domain-containing protein 7B; Zinc finger protein 67; Zinc finger protein Th-POK.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G037605 Zbtb7b.
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CL C0001; CH.
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SZ 544 AA; 58.9 kDa (calc.).
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SQ MGSPEDDLIGIPFPDHSSELLSCLNEQRQLGHLCDLTIRTQGLEYRTHRAVLAACSHYFK
SQ KLFTEGGGGTVMGTGGGGTASGGAGAGVCELDFVGPEALGALLEFAYTATLTTSSANMPA
SQ VLQAARLLEIPCVIAACMEILQGSGLEAPSPDEDDCERARQYLEAFATATTTASTSGMPN
SQ GEDSPPQVPLLPPPPPPPRPVARRSRKPRKAFLQTKGARANHLVPEAPTVLTHPLTYEEE
SQ EMVGRLGNSGGSGLGDSYSPPTGAASPAEGPLNYEVFEGEEEEEEMAYPPGYGLAQSNEP
SQ SLSPEELGSDEDPIDPDLMAYLSSLHQDALTPGLDGQDKLVRKRRSQMPQECPVCHKIIH
SQ GAGKLPRHMRTHTGEKPFACEVCGVRFTRNDKLKIHMRKHTGERPYSCPHCPARFLHSYD
SQ LKNHMHLHTGDRPYECHLCHKAFAKEDHLQRHLKGQNCLEVRTRRRRKDDVAAPHYPPPS
SQ TTTSSPAGLDLSNGHLDTFHLSLARFWEQSATTGPPVTTQGPPEEEEEEGTPTTPQAEGA
SQ MESS
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SC Swiss-Prot#Q64321
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FT 24 145 
PF00651; BTB.
FT 34 115 
PS50097; BTB.
FT 34 145 
SM00225; BTB_4.
FT 350 372 
SM00355; c2h2final6.
FT 350 377 
PS50157; ZINC_FINGER_C2H2_2.
FT 378 400 
PF00096; zf-C2H2.
FT 378 400 
SM00355; c2h2final6.
FT 378 405 
PS50157; ZINC_FINGER_C2H2_2.
FT 406 428 
PF00096; zf-C2H2.
FT 406 428 
SM00355; c2h2final6.
FT 406 433 PS50157; ZINC_FINGER_C2H2_2.
FT 434 454 SM00355; c2h2final6.
FT 434 458 PF00096; zf-C2H2.
FT 434 467 PS50157; ZINC_FINGER_C2H2_2.
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SF The C-terminus sequence of C-Krox is responsible for homodimerization [1];
SF Zinc finger domain and C-terminal domain are required for transactivation activity of c-KROX [1];
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IN T01427 p300; human, Homo sapiens.
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MX M01175 V$CKROX_Q2.
MX M02826 V$ZBTB7B_03.
MX M02930 V$ZBTB7B_04.
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BS R20577.
BS R19733.
BS R19734.
BS R20202.
BS R19736.
BS R20205.
BS R20207.
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DR TRANSPATH: MO000089898.
DR UniProtKB: Q64321; ZBT7B_MOUSE.
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RN [1]; RE0048585.
RX PUBMED: 8702912.
RA Galera P., Park R. W., Ducy P., Mattei M. G., Karsenty G.
RT c-Krox binds to several sites in the promoter of both mouse type I collagen genes. Structure/function study and developmental expression analysis.
RL J. Biol. Chem. 271:21331-21339 (1996).
RN [2]; RE0070225.
RX PUBMED: 20810990.
RA Zhang M., Zhang J., Rui J., Liu X.
RT p300-mediated acetylation stabilizes the Th-inducing POK factor.
RL J. Immunol. 185:3960-3969 (2010).
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