AC T09623
XX
ID T09623
XX
DT 08.11.2006 (created); kau.
DT 07.10.2014 (updated); spk.
CO Copyright (C), QIAGEN.
XX
FA ATF-6
XX
SY activating transcription factor 6; ATF6-alpha; cyclic-AMP-dependent transcription factor.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G002673 ATF6; HGNC: ATF6.
XX
CL C0008; bZIP.
XX
SZ 670 AA; 74.6 kDa (cDNA) (calc.).
XX
SQ MGEPAGVAGTMESPFSPGLFHRLDEDWDSALFAELGYFTDTDELQLEAANETYENNFDNL
SQ DFDLDLLPWESDIWDINNQICTVKDIKAEPQPLSPASSSYSVSSPRSVDSYSSTQHVPEE
SQ LDLSSSSQMSPLSLYGENSNSLSSPEPLKEDKPVTGSRNKTENGLTPKKKIQVNSKPSIQ
SQ PKPLLLPAAPKTQTNSSVPAKTIIIQTVPTLMPLAKQQPIISLQPAPTKGQTVLLSQPTV
SQ VQLQAPGVLPSAQPVLAVAGGVTQLPNHVVNVVPAPSANSPVNGKLSVTKPVLQSTMRNV
SQ GSDIAVLRRQQRMIKNRESACQSRKKKKEYMLGLEARLKAALSENEQLKKENGTLKRQLD
SQ EVVSENQRLKVPSPKRRVVCVMIVLAFIILNYGPMSMLEQDSRRMNPSVGPANQRRHLLG
SQ FSAKEAQDTSDGIIQKNSYRYDHSVSNDKALMVLTEEPLLYIPPPPCQPLINTTESLRLN
SQ HELRGWVHRHEVERTKSRRMTNNQQKTRILQGVVEQGSNSQLMAVQYTETTSSISRNSGS
SQ ELQVYYASPRSYQDFFEAIRRRGDTFYVVSFRRDHLLLPATTHNKTTRPKMSIVLPAINI
SQ NENVINGQDYEVMMQIDCQVMDTRILHIKSSSVPPYLRDQQRNQTNTFFGSPPAATEATH
SQ VVSTIPESLQ
XX
SC translated from EMBL #AF005887
XX
FT 263 566 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 304 368 
PF00170; bZIP transcription factor.
FT 304 368 
SM00338; brlzneu.
FT 306 369 
PS50217; BZIP.
XX
IN T09409 C/EBPbeta; mouse, Mus musculus.
IN T09410 C/EBPbeta; Mammalia.
IN T08699 XBP-1U; human, Homo sapiens.
IN T27866 Zhangfei; human, Homo sapiens.
XX
MX M00483 V$ATF6_01.
MX M00981 V$CREBATF_Q6.
XX
BS R11018.
BS R11019.
BS R11020.
BS R11021.
BS R11022.
BS R11023.
BS R11024.
BS R11025.
BS R11026.
BS R11027.
BS R11028.
BS R11029.
BS R11030.
BS R11031.
BS R11032.
BS R11033.
BS R11034.
BS R11035.
BS R11036.
BS R11037.
BS R26566.
XX
DR TRANSPATH: MO000090788.
DR EMBL: AF005887;
DR UniProtKB: P18850;
XX
RN [1]; RE0016854.
RX PUBMED: 10856300.
RA Wang Y., Shen J., Arenzana N., Tirasophon W., Kaufman R. J., Prywes R.
RT Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response.
RL J. Biol. Chem. 275:27013-27020 (2000).
RN [2]; RE0037394.
RX PUBMED: 11163209.
RA Ye J., Rawson R. B., Komuro R., Chen X., Dave U. P., Prywes R., Brown M. S., Goldstein J. L.
RT ER Stress Induces Cleavage of Membrane-Bound ATF6 by the Same Proteases that Process SREBPs
RL Mol. Cell 6:1355-1364 (2000).
RN [3]; RE0048287.
RX PUBMED: 12805554.
RA Newman J. R., Keating A. E.
RT Comprehensive identification of human bZIP interactions with coiled-coil arrays.
RL Science 300:2097-2101 (2003).
XX
//