AC T09962
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ID T09962
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DT 29.11.2006 (created); din.
DT 29.11.2006 (updated); din.
CO Copyright (C), QIAGEN.
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FA TFIIF-beta
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SY RAP30.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G003986 GTF2F2; HGNC: GTF2F2.
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SZ 249 AA; 28.4 kDa (cDNA) (calc.), 30 kDa (SDS) [6]
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SQ MAERGELDLTGAKQNTGVWLVKVPKYLSQQWAKASGRGEVGKLRIAKTQGRTEVSFTLNE
SQ DLANIHDIGGKPASVSAPREHPFVLQSVGGQTLTVFTESSSDKLSLEGIVVQRAECRPAA
SQ SENYMRLKRLQIEESSKPVRLSQQLDKVVTTNYKPVANHQYNIEYERKKKEDGKRARADK
SQ QHVLDMLFSAFEKHQYYNLKDLVDITKQPVVYLKEILKEIGVQNVKGIHKNTWELKPEYR
SQ HYQGEEKSD
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SC Swiss-Prot#P13984
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FT 1 110 
interaction with TFIIF-alpha [9].
FT 4 249 
PF02270; Transcription initiation factor IIF, beta.
FT 162 244 
cryptic DNA-binding [10].
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IN T08487 AR-isoform1; human, Homo sapiens.
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DR TRANSPATH: MO000093594.
DR EMBL: X16901;
DR EMBL: X59745;
DR UniProtKB: P13984;
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RN [1]; RE0005507.
RX PUBMED: 8758937.
RA Dubrovskaya V., Lavigne A.-C., Davidson I., Acker J., Staub A., Tora L.
RT Distinct domains of hTAFII100 are requireed for functional interactions with transcription factor TFIIbeta (RAP30) and incorporation into the TFIID complex
RL EMBO J. 15:3702-3712 (1996).
RN [2]; RE0005742.
RX PUBMED: 2477704.
RA Sopta M., Burton Z. F., Greenblatt J.
RT Structure and associated DNA-helicase activity of a general transcription initiation factor that binds to RNA polymerase II
RL Nature 341:410-414 (1989).
RN [3]; RE0005743.
RX PUBMED: 1840667.
RA Horikoshi M., Fujita H., Wang J., Takada R., Roeder R. G.
RT Nucleotide and amino acid sequences of RAP30
RL Nucleic Acids Res. 19:5436-5436 (1991).
RN [4]; RE0005748.
RX PUBMED: 1652156.
RA McCracken S., Greenblatt J.
RT Related RNA polymerase-binding regions in human RAP30/74 and Escherichia coli sigma70
RL Science 253:900-902 (1991).
RN [5]; RE0005749.
RX PUBMED: 1946469.
RA Flores O., Lu H., Killeen M., Greenblatt J., Burton Z. F., Reinberg D.
RT The small subunit of transcription factor IIF recruits RNA polymerase II into the preinitiation complex
RL Proc. Natl. Acad. Sci. USA 88:9999-10003 (1991).
RN [6]; RE0005750.
RX PUBMED: 2180931.
RA Flores O., Ha I., Reinberg D.
RT Factors involved in specific transcription by mammalian RNA polymerase II. Purification and subunit composition of transcription factor IIE
RL J. Biol. Chem. 265:5629-5634 (1990).
RN [7]; RE0005752.
RX PUBMED: 1729606.
RA Killeen M. T., Greenblatt J. F.
RT The general transcription factor RAP30 binds to RNA polymerase II and prevents it from binding nonspecifically to DNA
RL Mol. Cell. Biol. 12:30-37 (1992).
RN [8]; RE0005753.
RX PUBMED: 8376403.
RA Chang C.-H., Kostrub C. F., Burton Z. F.
RT RAP30/74 (transcription factor IIF) is required for promoter escape by RNA polymerase II
RL J. Biol. Chem. 268:20482-20489 (1993).
RN [9]; RE0005754.
RX PUBMED: 8441635.
RA Yonaha M., Aso T., Kobayashi Y., Vasavada H., Yasukochi Y., Weissman S. M., Kitajima S.
RT Domain structure of a human general transcription initiation factor, TFIIF
RL Nucleic Acids Res. 21:273-279 (1993).
RN [10]; RE0005755.
RX PUBMED: 7937895.
RA Tan S., Garrett K. P., Conaway R. C., Conaway J. W.
RT Cryptic DNA-binding domain in the C terminus of RNA polymerase II general transcription factor RAP30
RL Proc. Natl. Acad. Sci. USA 91:9808-9812 (1994).
RN [11]; RE0029221.
RX PUBMED: 9238003.
RA McEwan I. J., Gustafsson J.
RT Interaction of the human androgen receptor transactivation function with the general transcription factor TFIIF.
RL Proc. Natl. Acad. Sci. USA 94:8485-90 (1997).
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