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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T09992 XX ID T09992 XX DT 08.12.2006 (created); sts. CO Copyright (C), QIAGEN. XX FA PEA3-isoform1 XX SY E1A (adenovirus) enhancer-binding factor; E1A-F; ETV4; PEA-3. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G009201 Etv4. XX CL C0016; ETS. XX SZ 555 AA; 60.8 kDa (cDNA) (calc.), 63-70 kDa (SDS) XX SQ MTKSSNHNCLLRPENKPGLWGPGAQAASLRPSPATLVVSSPGHAEHPPAAPAQTPGPQVS SQ ASARGPGPVAGGSGRMERRMKGGYLDQRVPYTFCSKSPGNGSLGEALMVPQGKLMDPGSL SQ PPSDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTD SQ PALSCSRKPPLPYHHGEQCLYSRQIAIKSPAPGAPGQSPLQPFSRAEQQQSLLRASSSSQ SQ SHPGHGYLGEHSSVFQQPVDMCHSFTSPQGGGREPLPAPYQHQLSEPCPPYPQQNFKQEY SQ HDPLYEQAGQPASSQGGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFSGPS SQ PGDGVMGYGYEKSLRPFPDDVCIVPKKFEGDIKQEGIGAFREGPPYQRRGALQLWQFLVA SQ LLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQ SQ KVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPEL SQ TGPAPPFGHRGGYSY XX SC edited Swiss-Prot #P28322 XX FT 81 410 PF04621; PEA3 subfamily ETS-domain transcription fa. FT 410 511 DNA-binding domain [3]. FT 411 494 PF00178; Ets-domain. FT 411 496 SM00413; etsneu2. FT 412 492 PS50061; ETS_DOMAIN_3. FT 414 482 PS50140; HSF_ETS. XX IN T24830 Smad2; Mammalia. XX MX M00971 V$ETS_Q6. MX M01991 V$PEA3_01. MX M00655 V$PEA3_Q6. XX BS R18146. BS R26547. BS R02153. BS R01640. BS R26400. BS R04985. BS R26404. XX DR TRANSPATH: MO000094426. DR EMBL: X63190; MMPEA3. DR UniProtKB: P28322; ETV4_MOUSE. XX RN [1]; RE0000395. RX PUBMED: 2555163. RA Wasylyk C., Flores P., Gutman A., Wasylyk B. RT PEA3 is a nuclear target for transcription activation by non-nuclear oncogenes RL EMBO J. 8:3371-3378 (1989). RN [2]; RE0000614. RX PUBMED: 2163347. RA Gunther C. V., Nye J. A., Bryner R. S., Graves B. J. RT Sequence-specific DNA binding of the proto-oncoprotein ets-1 defines a transcriptional activator sequence within the long terminal repeat of the Moloney murine sarcoma virus RL Genes Dev. 4:667-679 (1990). RN [3]; RE0000804. RX PUBMED: 1547944. RA Xin J.-H., Cowie A., Lachance P., Hassell J. A. RT Molecular cloning and characterization of PEA3, a new member of the Ets oncogene family that is differentially expressed in mouse embryonic cells RL Genes Dev. 6:481-496 (1992). RN [4]; RE0001866. RX PUBMED: 2114554. RA Wasylyk B., Wasylyk C., Flores P., Begue A., Leprince D., Stehelin D. RT The c-ets proto-oncogenes encode transcription factors that cooperate with c-Fos and c-Jun for transcriptional activation RL Nature 346:191-193 (1990). RN [5]; RE0002339. RX PUBMED: 2842750. RA Martin M. E., Piette J., Yaniv M., Tang W.-J., Folk W. R. RT Activator of the polyomavirus enhancer by a murine activator protein 1 (AP1) homolog and two contiguous proteins RL Proc. Natl. Acad. Sci. USA 85:5839-5843 (1988). RN [6]; RE0002743. RX PUBMED: 2162765. RA Gutman A., Wasylyk B. RT The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 binding sites RL EMBO J. 9:2241-2246 (1990). RN [7]; RE0005329. RX PUBMED: 2167444. RA Rochford R., Davis C. T., Yoshimoto K., Villarreal L. P. RT Minimal subenhancer requirements for high-level polyomavirus DNA replication: A cell-specific synergy of PEA3 and PEA1 sites RL Mol. Cell. Biol. 10:4996-5001 (1990). RN [8]; RE0016582. RX PUBMED: 2119494. RA Rorth P., C. Nerlov, F. Blasi, Johnsen M. RT Transcription factor PEA3 participates in the induction of urokinase plasminogen activator transcription in murine keratinocytes stimulated with epidermal growth factor or phorbol-ester. RL Nucleic Acids Res. 18:5009-5017 (1990). XX //