AC T09992
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ID T09992
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DT 08.12.2006 (created); sts.
CO Copyright (C), QIAGEN.
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FA PEA3-isoform1
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SY E1A (adenovirus) enhancer-binding factor; E1A-F; ETV4; PEA-3.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G009201 Etv4.
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CL C0016; ETS.
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SZ 555 AA; 60.8 kDa (cDNA) (calc.), 63-70 kDa (SDS)
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SQ MTKSSNHNCLLRPENKPGLWGPGAQAASLRPSPATLVVSSPGHAEHPPAAPAQTPGPQVS
SQ ASARGPGPVAGGSGRMERRMKGGYLDQRVPYTFCSKSPGNGSLGEALMVPQGKLMDPGSL
SQ PPSDSEDLFQDLSHFQETWLAEAQVPDSDEQFVPDFHSENLAFHSPTTRIKKEPQSPRTD
SQ PALSCSRKPPLPYHHGEQCLYSRQIAIKSPAPGAPGQSPLQPFSRAEQQQSLLRASSSSQ
SQ SHPGHGYLGEHSSVFQQPVDMCHSFTSPQGGGREPLPAPYQHQLSEPCPPYPQQNFKQEY
SQ HDPLYEQAGQPASSQGGVSGHRYPGAGVVIKQERTDFAYDSDVPGCASMYLHPEGFSGPS
SQ PGDGVMGYGYEKSLRPFPDDVCIVPKKFEGDIKQEGIGAFREGPPYQRRGALQLWQFLVA
SQ LLDDPTNAHFIAWTGRGMEFKLIEPEEVARLWGIQKNRPAMNYDKLSRSLRYYYEKGIMQ
SQ KVAGERYVYKFVCEPEALFSLAFPDNQRPALKAEFDRPVSEEDTVPLSHLDESPAYLPEL
SQ TGPAPPFGHRGGYSY
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SC edited Swiss-Prot #P28322
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FT 81 410 
PF04621; PEA3 subfamily ETS-domain transcription fa.
FT 410 511 
DNA-binding domain [3].
FT 411 494 
PF00178; Ets-domain.
FT 411 496 
SM00413; etsneu2.
FT 412 492 
PS50061; ETS_DOMAIN_3.
FT 414 482 
PS50140; HSF_ETS.
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IN T24830 Smad2; Mammalia.
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MX M00971 V$ETS_Q6.
MX M01991 V$PEA3_01.
MX M00655 V$PEA3_Q6.
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BS R18146.
BS R26547.
BS R02153.
BS R01640.
BS R26400.
BS R04985.
BS R26404.
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DR TRANSPATH: MO000094426.
DR EMBL: X63190; MMPEA3.
DR UniProtKB: P28322; ETV4_MOUSE.
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RN [1]; RE0000395.
RX PUBMED: 2555163.
RA Wasylyk C., Flores P., Gutman A., Wasylyk B.
RT PEA3 is a nuclear target for transcription activation by non-nuclear oncogenes
RL EMBO J. 8:3371-3378 (1989).
RN [2]; RE0000614.
RX PUBMED: 2163347.
RA Gunther C. V., Nye J. A., Bryner R. S., Graves B. J.
RT Sequence-specific DNA binding of the proto-oncoprotein ets-1 defines a transcriptional activator sequence within the long terminal repeat of the Moloney murine sarcoma virus
RL Genes Dev. 4:667-679 (1990).
RN [3]; RE0000804.
RX PUBMED: 1547944.
RA Xin J.-H., Cowie A., Lachance P., Hassell J. A.
RT Molecular cloning and characterization of PEA3, a new member of the Ets oncogene family that is differentially expressed in mouse embryonic cells
RL Genes Dev. 6:481-496 (1992).
RN [4]; RE0001866.
RX PUBMED: 2114554.
RA Wasylyk B., Wasylyk C., Flores P., Begue A., Leprince D., Stehelin D.
RT The c-ets proto-oncogenes encode transcription factors that cooperate with c-Fos and c-Jun for transcriptional activation
RL Nature 346:191-193 (1990).
RN [5]; RE0002339.
RX PUBMED: 2842750.
RA Martin M. E., Piette J., Yaniv M., Tang W.-J., Folk W. R.
RT Activator of the polyomavirus enhancer by a murine activator protein 1 (AP1) homolog and two contiguous proteins
RL Proc. Natl. Acad. Sci. USA 85:5839-5843 (1988).
RN [6]; RE0002743.
RX PUBMED: 2162765.
RA Gutman A., Wasylyk B.
RT The collagenase gene promoter contains a TPA and oncogene-responsive unit encompassing the PEA3 and AP-1 binding sites
RL EMBO J. 9:2241-2246 (1990).
RN [7]; RE0005329.
RX PUBMED: 2167444.
RA Rochford R., Davis C. T., Yoshimoto K., Villarreal L. P.
RT Minimal subenhancer requirements for high-level polyomavirus DNA replication: A cell-specific synergy of PEA3 and PEA1 sites
RL Mol. Cell. Biol. 10:4996-5001 (1990).
RN [8]; RE0016582.
RX PUBMED: 2119494.
RA Rorth P., C. Nerlov, F. Blasi, Johnsen M.
RT Transcription factor PEA3 participates in the induction of urokinase plasminogen activator transcription in murine keratinocytes stimulated with epidermal growth factor or phorbol-ester.
RL Nucleic Acids Res. 18:5009-5017 (1990).
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