AC T10208
XX
ID T10208
XX
DT 01.02.2007 (created); man.
DT 19.07.2012 (updated); mkl.
CO Copyright (C), QIAGEN.
XX
FA GATA-6-isoform1
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SY GATA binding protein 6; GATA6.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G004483 Gata6.
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CL C0003; CC (g).
XX
SZ 589 AA; 59.3 kDa (cDNA) (calc.).
XX
SQ MALTDGGWCLPKRFGAAAADAGDSGPFPAREPSSPLSPISSSSSSCSRGGDRGPCGASNC
SQ RTPQLDAEAVAGPPGRSLLLSPYASHPFAAAHGAAAPGVAGPGSALSTWEDLLLFTDLDQ
SQ AATASKLLWSSRGAKLSPFAAEQPEEMYQTLAALSSQGPAAYDGAPGGFVHSAAAAAAAA
SQ AAASSPVYVPTTRVGSMLSGLPYLQGAGSGPSNHAGGAGAHPGWSQASADSPPYGGGGAA
SQ GGGAAGPGGAGSATAHASARFPYSPSPPMANGAARDPGGYVAAGGTGAGSVSGGGGSLAA
SQ MGGREHQYSSLSAARPLNGTYHHHHHHHPTYSPYMAAPLTPAWPAGPFETPVLHSLQGRA
SQ GAPLPVPRGPSTDLLEDLSESRECVNCGSIQTPLWRRDGTGHYLCNACGLYSKMNGLSRP
SQ LIKPQKRVPSSRRLGLSCANCHTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMKKE
SQ GIQTRKRKPKNINKSKACSGNSSGSVPMTPTSSSSNSDDCTKNTSPSTQATTSGVGASVM
SQ SAVGENANPENSDLKYSGQDGLYIGVSLSSPAEVTSSVRQDSWCALALA
XX
SC Swiss-Prot#Q61169-1
XX
FT 1 230 PF05349; GATA-type transcription activator, N-termina.
FT 233 284 SM00401; ZnF_GATA.
FT 233 287 PS50114; GATA_ZN_FINGER_2.
FT 239 273 PF00320; GATA zinc finger.
FT 287 337 SM00401; ZnF_GATA.
FT 287 340 PS50114; GATA_ZN_FINGER_2.
FT 293 327 PF00320; GATA zinc finger.
XX
IN T19612 DRIP205; mouse, Mus musculus.
IN T10209 TTF-1; rat, Rattus norvegicus.
IN T10215 TTF-1; mouse, Mus musculus.
IN T10505 TTF-1; Mammalia.
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MX M00462 V$GATA6_01.
MX M02757 V$GATA6_04.
MX M02861 V$GATA6_05.
MX M03216 V$GATA6_Q5.
MX M00789 V$GATA_Q6.
XX
BS R32634.
BS R22886.
BS R31555.
BS R13147.
BS R13156.
BS R08290.
BS R13256.
BS R13257.
BS R31174.
BS R30320.
BS R29127.
XX
DR TRANSPATH: MO000097976.
DR EMBL: S82462;
DR EMBL: U51335;
DR UniProtKB: Q61169-1;
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RN [1]; RE0013563.
RX PUBMED: 8660897.
RA Morrisey E. E., Ip H. S., Lu M. M., Parmacek M. S.
RT GATA-6: a zinc finger transcription factor that is expressed in multiple cell lineages derived from lateral mesoderm.
RL Dev. Biol. 177:309-322 (1996).
RN [2]; RE0013564.
RX PUBMED: 8812463.
RA Narita N., Heikinheimo M., Bielinska M., White R. A., Wilson D. B.
RT The gene for transcription factor GATA-6 resides on mouse chromosome 18 and is expressed in myocardium and vascular smooth muscle.
RL Genomics 36:345-348 (1996).
RN [3]; RE0018174.
RX PUBMED: 11733512.
RA Liu C., Glasser S. W., Wan H., Whitsett J. A.
RT GATA-6 and thyroid transcription factor-1 directly interact and regulate surfactant protein-C gene expression.
RL J. Biol. Chem. 277:4519-4525 (2002).
RN [4]; RE0022227.
RX PUBMED: 11914369.
RA Weidenfeld J., Shu W., Zhang L., Millar S. E., Morrisey E. E.
RT The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium.
RL J. Biol. Chem. 277:21061-21070 (2002).
RN [5]; RE0029104.
RX PUBMED: 11724781.
RA Crawford S. E., Qi C., Misra P., Stellmach V., Rao M. S., Engel J. D., Zhu Y., Reddy J. K.
RT Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factors.
RL J. Biol. Chem. 277:3585-92 (2002).
RN [6]; RE0065693.
RX PUBMED: 18768929.
RA Zhou B., Francis T. A., Yang H., Tseng W., Zhong Q., Frenkel B., Morrisey E. E., Ann D. K., Minoo P., Crandall E. D., Borok Z.
RT GATA-6 mediates transcriptional activation of aquaporin-5 through interactions with Sp1.
RL Am. J. Physiol. Cell Physiol. 295:C1141-50 (2008).
XX
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