AC T10238
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ID T10238
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DT 18.01.2006 (created); anu.
DT 03.06.2015 (updated); msr.
CO Copyright (C), QIAGEN.
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FA ATF-2
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SY activating transcription factor 2; ATF-2; ATF2; CRE-BP; CREB2; D130078H02Rik; mXBP.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G009504 Atf2.
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CL C0008; bZIP; 1.1.1.3.1.
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CP present in 3T3-L1 cells [2].
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IN T10542 p300; mouse, Mus musculus.
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MX M01862 V$ATF2_Q5.
MX M07312 V$ATF2_Q6.
MX M00981 V$CREBATF_Q6.
MX M00041 V$CREBP1CJUN_01.
MX M00040 V$CREBP1_01.
MX M00179 V$CREBP1_Q2.
MX M00801 V$CREB_Q3.
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BS R11554.
BS R32890.
BS R31456.
BS R29487.
BS R68048.
BS R24796.
BS R23090.
BS R21414.
BS R66121.
BS R64220.
BS R01216.
BS R22530.
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DR TRANSPATH: MO000057397.
DR UniProtKB: P16951;
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RN [1]; RE0035756.
RX PUBMED: 15192015.
RA Zhu F., Zhang Y., Bode A. M., Dong Z.
RT Involvement of ERKs and mitogen- and stress-activated protein kinase in UVC-induced phosphorylation of ATF2 in JB6 cells.
RL Carcinogenesis 25:1847-1852 (2004).
RN [2]; RE0049352.
RX PUBMED: 11243868.
RA Lee M. Y., Kong H. J., Cheong J.
RT Regulation of activating transcription factor-2 in early stage of the adipocyte differentiation program.
RL Biochem. Biophys. Res. Commun. 281:1241-1247 (2001).
RN [3]; RE0050737.
RX PUBMED: 17700520.
RA Maekawa T., Sano Y., Shinagawa T., Rahman Z., Sakuma T., Nomura S., Licht J. D., Ishii S.
RT ATF-2 controls transcription of Maspin and GADD45alpha genes independently from p53 to suppress mammary tumors.
RL Oncogene 27:1045-1054 (2007).
RN [4]; RE0053674.
RX PUBMED: 16818236.
RA Lu C., Zhu F., Cho Y. Y., Tang F., Zykova T., Ma W. Y., Bode A. M., Dong Z.
RT Cell apoptosis: requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3.
RL Mol. Cell 23:121-132 (2006).
RN [5]; RE0055116.
RX PUBMED: 9436983.
RA Kawasaki H., Song J., Eckner R., Ugai H., Chiu R., Taira K., Shi Y., Jones N., Yokoyama K. K.
RT p300 and ATF-2 are components of the DRF complex, which regulates retinoic acid- and E1A-mediated transcription of the c-jun gene in F9 cells.
RL Genes Dev. 12:233-245 (1998).
RN [6]; RE0068114.
RX PUBMED: 12110590.
RA Ouwens D. M., de Ruiter N. D., Van der Zon G. C., Carter A. P., Schouten J., van der Burgt C., Kooistra K., Bos J. L., Maassen J. A., van Dam H.
RT Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38.
RL EMBO J. 21:3782-3793 (2002).
RN [7]; RE0070678.
RX PUBMED: 20531401.
RA Weintz G., Olsen J. V., Fruhauf K., Niedzielska M., Amit I., Jantsch J., Mages J., Frech C., Dolken L., Mann M., Lang R.
RT The phosphoproteome of toll-like receptor-activated macrophages.
RL Mol. Syst. Biol. 6:371 (2010).
RN [8]; RE0071159.
RX PUBMED: 19223432.
RA Shinohara H., Yamasaki S., Maeda S., Saito T., Kurosaki T.
RT Regulation of NF-kappaB-dependent T cell activation and development by MEKK3.
RL Int. Immunol. 21:393-401 (2009).
RN [9]; RE0072504.
RX PUBMED: 21444723.
RA Pillai V. B., Sundaresan N. R., Samant S. A., Wolfgeher D., Trivedi C. M., Gupta M. P.
RT Acetylation of a conserved lysine residue in the ATP binding pocket of p38 augments its kinase activity during hypertrophy of cardiomyocytes.
RL Mol. Cell. Biol. 31:2349-2363 (2011).
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