AC T10542
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ID T10542
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DT 15.05.2002 (created); spi.
DT 06.05.2015 (updated); hna.
CO Copyright (C), QIAGEN.
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FA p300
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SY A430090G16; A730011L11; E1A binding protein p300; E1A-associated protein p300; EP300; KAT3B; p300; p300 HAT; p300 transcription coactivator homolog; p300-HAT.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G005254 Ep300.
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IN T00018 AhR; mouse, Mus musculus.
IN T06598 AML-1; mouse, Mus musculus.
IN T01797 arnt; mouse, Mus musculus.
IN T10238 ATF-2; mouse, Mus musculus.
IN T02984 beta-catenin; mouse, Mus musculus.
IN T14513 beta-catenin; Mammalia.
IN T09541 c-Krox; mouse, Mus musculus.
IN T09409 C/EBPbeta; mouse, Mus musculus.
IN T02002 Cdx-2; mouse, Mus musculus.
IN T00259 ER-alpha; mouse, Mus musculus.
IN T00335 GR; mouse, Mus musculus.
IN T00436 JunB; mouse, Mus musculus.
IN T09551 LEF-1; Mammalia.
IN T09576 LEF-1; mouse, Mus musculus.
IN T10173 M-Twist; mouse, Mus musculus.
IN T15781 mef-2a; mouse, Mus musculus.
IN T09547 MEF-2C; mouse, Mus musculus.
IN T17720 MEF-2D; mouse, Mus musculus.
IN T10644 MTF-1; mouse, Mus musculus.
IN T00526 MyoD; mouse, Mus musculus.
IN T09437 NF-kappaB1; mouse, Mus musculus.
IN T05877 NPAS2; mouse, Mus musculus.
IN T01806 p53; mouse, Mus musculus.
IN T06293 p63; mouse, Mus musculus.
IN T14488 PARP; mouse, Mus musculus.
IN T00681 Pax-6; mouse, Mus musculus.
IN T08431 PPARalpha; mouse, Mus musculus.
IN T00717 RAR; mouse, Mus musculus.
IN T00595 RelA-p65; mouse, Mus musculus.
IN T09519 SF-1-isoform1; mouse, Mus musculus.
IN T13998 Smad4; Mammalia.
IN T00752 Sp1; mouse, Mus musculus.
IN T05840 Sp3; mouse, Mus musculus.
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MX M00033 V$P300_01.
MX M07266 V$P300_Q5.
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BS R67496.
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DR TRANSPATH: MO000031227.
DR UniProtKB: B2RWS6;
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RN [1]; RE0039427.
RX PUBMED: 9606182.
RA Kitabayashi I., Yokoyama A., Shimizu K., Ohki M.
RT Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation
RL EMBO J. 17:2994-3004 (1998).
RN [2]; RE0040875.
RX PUBMED: 9407140.
RA Dowell P., Ishmael J. E., Avram D., Peterson V. J., Nevrivy D. J., Leid M.
RT p300 functions as a coactivator for the peroxisome proliferator-activated receptor alpha
RL J. Biol. Chem. 272:33435-43 (1997).
RN [3]; RE0042226.
RX PUBMED: 12960163.
RA Hassa P. O., Buerki C., Lombardi C., Imhof R., Hottiger M. O.
RT Transcriptional coactivation of nuclear factor-kappaB-dependent gene expression by p300 is regulated by poly(ADP)-ribose polymerase-1
RL J. Biol. Chem. 278:45145-53 (2003).
RN [4]; RE0042632.
RX PUBMED: 10025406.
RA Hamamori Y., Sartorelli V., Ogryzko V., Puri P. L., Wu H. Y., Wang J. Y., Nakatani Y., Kedes L.
RT Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A
RL Cell 96:405-13 (1999).
RN [5]; RE0047049.
RX PUBMED: 14687547.
RA Gold D. A., Baek S. H., Schork N. J., Rose D. W., Larsen D. D., Sachs B. D., Rosenfeld M. G., Hamilton B. A.
RT RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways
RL Neuron 40:1119-31 (2003).
RN [6]; RE0047660.
RX PUBMED: 12727880.
RA Wiper-Bergeron N., Wu D., Pope L., Schild-Poulter C., Hache R. J.
RT Stimulation of preadipocyte differentiation by steroid through targeting of an HDAC1 complex.
RL EMBO J. 22:2135-2145 (2003).
RN [7]; RE0047972.
RX PUBMED: 10506141.
RA Hussain M. A., Habener J. F.
RT Glucagon gene transcription activation mediated by synergistic interactions of pax-6 and cdx-2 with the p300 co-activator.
RL J. Biol. Chem. 274:28950-28957 (1999).
RN [8]; RE0048805.
RX PUBMED: 15308641.
RA Narayanan K., Srinivas R., Peterson M. C., Ramachandran A., Hao J., Thimmapaya B., Scherer P. E., George A.
RT Transcriptional regulation of dentin matrix protein 1 by JunB and p300 during osteoblast differentiation.
RL J. Biol. Chem. 279:44294-44302 (2004).
RN [9]; RE0049085.
RX PUBMED: 16287857.
RA Chen W. Y., Juan L. J., Chung B. C.
RT SF-1 (nuclear receptor 5A1) activity is activated by cyclic AMP via p300-mediated recruitment to active foci, acetylation, and increased DNA binding.
RL Mol. Cell. Biol. 25:10442-10453 (2005).
RN [10]; RE0049146.
RX PUBMED: 16287841.
RA Schuh A. H., Tipping A. J., Clark A. J., Hamlett I., Guyot B., Iborra F. J., Rodriguez P., Strouboulis J., Enver T., Vyas P., Porcher C.
RT ETO-2 associates with SCL in erythroid cells and megakaryocytes and provides repressor functions in erythropoiesis.
RL Mol. Cell. Biol. 25:10235-10250 (2005).
RN [11]; RE0049233.
RX PUBMED: 12888559.
RA Brouillard F., Cremisi C. E.
RT Concomitant increase of histone acetyltransferase activity and degradation of p300 during retinoic acid-induced differentiation of F9 cells.
RL J. Biol. Chem. 278:39509-39516 (2003).
RN [12]; RE0055116.
RX PUBMED: 9436983.
RA Kawasaki H., Song J., Eckner R., Ugai H., Chiu R., Taira K., Shi Y., Jones N., Yokoyama K. K.
RT p300 and ATF-2 are components of the DRF complex, which regulates retinoic acid- and E1A-mediated transcription of the c-jun gene in F9 cells.
RL Genes Dev. 12:233-245 (1998).
RN [13]; RE0065548.
RX PUBMED: 19574399.
RA Chen J., An B. S., Cheng L., Hammond G. L., Leung P. C.
RT Gonadotropin-releasing hormone-mediated phosphorylation of estrogen receptor-alpha contributes to fosB expression in mouse gonadotrophs.
RL Endocrinology 150:4583-4593 (2009).
RN [14]; RE0070019.
RX PUBMED: 19949111.
RA Liu Z., Mai A., Sun J.
RT Lysine acetylation regulates Bruton's tyrosine kinase in B cell activation.
RL J. Immunol. 184:244-254 (2010).
RN [15]; RE0070225.
RX PUBMED: 20810990.
RA Zhang M., Zhang J., Rui J., Liu X.
RT p300-mediated acetylation stabilizes the Th-inducing POK factor.
RL J. Immunol. 185:3960-3969 (2010).
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