TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T06293 XX ID T06293 XX DT 15.10.2004 (created); oke. DT 15.04.2016 (updated); hna. CO Copyright (C), QIAGEN. XX FA p63 XX SY KET; p63; p73L; TP63; transformation related protein 63; Trp63. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G009623 Trp63. XX CL C0057; P53; XX SF generic entry for factors encoded by the mouse p63 (P73L) gene; SF several alternative products are known, p63alpha T06168, p63beta T06290, p63gamma T06291, DeltaNp63alpha T06011, DeltaNp63beta T06010, DeltaNp63gamma T06292 [2]; SF DeltaN variants lack N-terminal transactivation domain [2]; SF variants alpha, beta, gamma refer to different C termini [2]; XX FF is required for limb and epidermal morphogenesis [1] [2]; FF mice that lack p63 gene: limbs are truncated or absent, skin does not express differentiation markers, teeth and mammary glands are absent [1] [2]; XX IN T10542 p300; mouse, Mus musculus. XX MX M00761 V$P53DECAMER_Q2. MX M01656 V$P63_01. XX BS R26473. BS R70389. BS R70393. BS R61732. BS R69979. BS R69980. BS R69981. BS R69982. BS R70388. BS R67995. BS R67997. BS R61734. BS R72785. BS R72786. XX DR TRANSPATH: MO000044173. DR EMBL: AF533892; AF533892. XX RN [1]; RE0024978. RX PUBMED: 10227293. RA Mills A. A., Zheng B., Wang X. J., Vogel H., Roop D. R., Bradley A. RT p63 is a p53 homologue required for limb and epidermal morphogenesis. RL Nature 398:708-713 (1999). RN [2]; RE0024981. RX PUBMED: 10227294. RA Yang A., Schweitzer R., Sun D., Kaghad M., Walker N., Bronson R. T., Tabin C., Sharpe A., Caput D., Crum C., McKeon F. RT p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. RL Nature 398:714-718 (1999). XX //