AC T06292
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ID T06292
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DT 15.10.2004 (created); oke.
DT 20.01.2009 (updated); ask.
CO Copyright (C), QIAGEN.
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FA DeltaNp63gamma
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SY DN p63 gamma; DN p63gamma; p63 DN gamma.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G009623 Trp63.
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CL C0057; P53; 6.3.1.0.2.6.
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SZ 389 AA; 44.0 kDa (calc.).
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SQ MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS
SQ TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK
SQ VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ
SQ YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV
SQ LGRRCFEARICACPGRDRKADEDSIRKQQVSDSAKNGDAFRQNTHGIQMTSIKKRRSPDD
SQ ELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKHLLSACFRN
SQ ELVEPRGEAPTQSDVFFRHSNPPNHSVYP
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SC translated from EMBL #AF075437
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FT 58 347 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 69 265 
PF00870; P53 DNA-binding domain.
FT 293 334 
PF07710; P53 tetramerisation motif.
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SF one of the alternative products of the mouse trp63 gene: p63alpha T06168, p63beta T06290, p63gamma T06291, DeltaNp63alpha T06011, DeltaNp63beta T06010, DeltaNp63gamma T06292 [1];
SF lacks coding parts of exons 11, 12, 13, 14, 15 in comparison with DeltaNp63alpha [1];
SF lacks transactivation (TA) domain [1];
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MX M00761 V$P53DECAMER_Q2.
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BS R26473.
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DR TRANSPATH: MO000044178.
DR EMBL: AF075437;
DR EMBL: AF533892;
DR UniProtKB: O88898-6;
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RN [1]; RE0024981.
RX PUBMED: 10227294.
RA Yang A., Schweitzer R., Sun D., Kaghad M., Walker N., Bronson R. T., Tabin C., Sharpe A., Caput D., Crum C., McKeon F.
RT p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development.
RL Nature 398:714-718 (1999).
RN [2]; RE0050255.
RX PUBMED: 16861923.
RA Rossi M., De Simone M., Pollice A., Santoro R., La Mantia G., Guerrini L., Calabro V.
RT Itch/AIP4 associates with and promotes p63 protein degradation.
RL Cell Cycle 5:1816-1822 (2006).
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