TRANSFAC-Logo

TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T06291 XX ID T06291 XX DT 15.10.2004 (created); oke. DT 06.05.2013 (updated); yre. CO Copyright (C), QIAGEN. XX FA p63gamma XX SY p63 TA gamma; TAp63gamma. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G009623 Trp63. XX CL C0057; P53; 6.3.1.0.2.5. XX SZ 483 AA; 55.0 kDa (calc.). XX SQ MNFETSRCATLQYCPDPYIQRFIETPAHFSWKESYYRSAMSQSTQTSEFLSPEVFQHIWD SQ FLEQPICSVQPIELNFVDEPSENGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSM SQ DQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVS SQ FQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEV SQ VKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFT SQ TVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIR SQ KQQVSDSAKNGDAFRQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELM SQ QYLPQHTIETYRQQQQQQHQHLLQKHLLSACFRNELVEPRGEAPTQSDVFFRHSNPPNHS SQ VYP XX SC translated from EMBL #AF075434 XX FT 152 441 PF00478; IMP dehydrogenase / GMP reductase domain. FT 163 359 PF00870; P53 DNA-binding domain. FT 387 428 PF07710; P53 tetramerisation motif. XX SF one of the alternative products of the mouse trp63 gene: p63alpha T06168, p63beta T06290, p63gamma T06291, DeltaNp63alpha T06011, DeltaNp63beta T06010, DeltaNp63gamma T06292 [1]; SF lacks coding parts of exons 11, 12, 13, 14, 15 in comparison with p63alpha [1]; XX MX M00761 V$P53DECAMER_Q2. XX DR TRANSPATH: MO000044177. DR EMBL: AF075434; DR EMBL: AF533892; DR UniProtKB: O88898-5; XX RN [1]; RE0024981. RX PUBMED: 10227294. RA Yang A., Schweitzer R., Sun D., Kaghad M., Walker N., Bronson R. T., Tabin C., Sharpe A., Caput D., Crum C., McKeon F. RT p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. RL Nature 398:714-718 (1999). RN [2]; RE0050255. RX PUBMED: 16861923. RA Rossi M., De Simone M., Pollice A., Santoro R., La Mantia G., Guerrini L., Calabro V. RT Itch/AIP4 associates with and promotes p63 protein degradation. RL Cell Cycle 5:1816-1822 (2006). XX //