AC T06291
XX
ID T06291
XX
DT 15.10.2004 (created); oke.
DT 06.05.2013 (updated); yre.
CO Copyright (C), QIAGEN.
XX
FA p63gamma
XX
SY p63 TA gamma; TAp63gamma.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G009623 Trp63.
XX
CL C0057; P53; 6.3.1.0.2.5.
XX
SZ 483 AA; 55.0 kDa (calc.).
XX
SQ MNFETSRCATLQYCPDPYIQRFIETPAHFSWKESYYRSAMSQSTQTSEFLSPEVFQHIWD
SQ FLEQPICSVQPIELNFVDEPSENGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSM
SQ DQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVS
SQ FQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEV
SQ VKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFT
SQ TVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIR
SQ KQQVSDSAKNGDAFRQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELM
SQ QYLPQHTIETYRQQQQQQHQHLLQKHLLSACFRNELVEPRGEAPTQSDVFFRHSNPPNHS
SQ VYP
XX
SC translated from EMBL #AF075434
XX
FT 152 441 PF00478; IMP dehydrogenase / GMP reductase domain.
FT 163 359 PF00870; P53 DNA-binding domain.
FT 387 428 PF07710; P53 tetramerisation motif.
XX
SF one of the alternative products of the mouse trp63 gene: p63alpha T06168, p63beta T06290, p63gamma T06291, DeltaNp63alpha T06011, DeltaNp63beta T06010, DeltaNp63gamma T06292 [1];
SF lacks coding parts of exons 11, 12, 13, 14, 15 in comparison with p63alpha [1];
XX
MX M00761 V$P53DECAMER_Q2.
XX
DR TRANSPATH: MO000044177.
DR EMBL: AF075434;
DR EMBL: AF533892;
DR UniProtKB: O88898-5;
XX
RN [1]; RE0024981.
RX PUBMED: 10227294.
RA Yang A., Schweitzer R., Sun D., Kaghad M., Walker N., Bronson R. T., Tabin C., Sharpe A., Caput D., Crum C., McKeon F.
RT p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development.
RL Nature 398:714-718 (1999).
RN [2]; RE0050255.
RX PUBMED: 16861923.
RA Rossi M., De Simone M., Pollice A., Santoro R., La Mantia G., Guerrini L., Calabro V.
RT Itch/AIP4 associates with and promotes p63 protein degradation.
RL Cell Cycle 5:1816-1822 (2006).
XX
//