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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T06010 XX ID T06010 XX DT 09.06.2004 (created); cch. DT 20.01.2009 (updated); ask. CO Copyright (C), QIAGEN. XX FA DeltaN p63beta XX SY DN p63 beta; DN p63beta; KET; p63; p63 DN beta; p73L; TAp63; TP63; transformation related protein 63; Trp53rp1; Trp63. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G009623 Trp63. XX CL C0057; P53; 6.3.1.0.2.4. XX SZ 461 AA; 51.5 kDa (calc.). XX SQ MLYLENNAQTQFSEPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSS SQ TFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIK SQ VMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQ SQ YVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQV SQ LGRRCFEARICACPGRDRKADEDSIRKQQVSDSAKNGDGTKRPFRQNTHGIQMTSIKKRR SQ SPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSMQ SQ SQSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTMPEGMGANIPMMGTHMPMAG SQ DMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIVRIWQV XX SC translated from EMBL #AF075438 XX FT 58 351 PF00478; IMP dehydrogenase / GMP reductase domain. FT 69 265 PF00870; P53 DNA-binding domain. FT 297 338 PF07710; P53 tetramerisation motif. XX SF one of the alternative products of the mouse trp63 gene: p63alpha T06168, p63beta T06290, p63gamma T06291, DeltaNp63alpha T06011, DeltaNp63beta T06010, DeltaNp63gamma T06292 [1]; SF lacks exon 13 in comparison with DeltaNp63alpha [1]; SF lacks transactivation (TA) domain [1]; XX MX M00761 V$P53DECAMER_Q2. XX BS R26473. XX DR TRANSPATH: MO000042313. DR EMBL: AF075438; DR EMBL: AF533892; AF533892. DR UniProtKB: O88898-4; XX RN [1]; RE0024981. RX PUBMED: 10227294. RA Yang A., Schweitzer R., Sun D., Kaghad M., Walker N., Bronson R. T., Tabin C., Sharpe A., Caput D., Crum C., McKeon F. RT p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. RL Nature 398:714-718 (1999). RN [2]; RE0050255. RX PUBMED: 16861923. RA Rossi M., De Simone M., Pollice A., Santoro R., La Mantia G., Guerrini L., Calabro V. RT Itch/AIP4 associates with and promotes p63 protein degradation. RL Cell Cycle 5:1816-1822 (2006). XX //