AC T06290
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ID T06290
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DT 15.10.2004 (created); oke.
DT 29.06.2007 (updated); man.
CO Copyright (C), QIAGEN.
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FA p63beta
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SY p63 TA beta; TAp63beta.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G009623 Trp63.
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CL C0057; P53; 6.3.1.0.2.3.
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SZ 555 AA; 62.4 kDa (calc.).
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SQ MNFETSRCATLQYCPDPYIQRFIETPAHFSWKESYYRSAMSQSTQTSEFLSPEVFQHIWD
SQ FLEQPICSVQPIELNFVDEPSENGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSM
SQ DQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVS
SQ FQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEV
SQ VKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFT
SQ TVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIR
SQ KQQVSDSAKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKES
SQ LELMQYLPQHTIETYRQQQQQQHQHLLQKQTSMQSQSSYGNSSPPLNKMNSMNKLPSVSQ
SQ LINPQQRNALTPTTMPEGMGANIPMMGTHMPMAGDMNGLSPTQALPPPLSMPSTSHCTPP
SQ PPYPTDCSIVRIWQV
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SC Swiss-Prot#O88898-3
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FT 152 445 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 163 359 
PF00870; P53 DNA-binding domain.
FT 391 432 
PF07710; P53 tetramerisation motif.
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SF one of the alternative products of the mouse trp63 gene: p63alpha T06168, p63beta T06290, p63gamma T06291, DeltaNp63alpha T06011, DeltaNp63beta T06010, DeltaNp63gamma T06292 [1];
SF lacks exon 13 in comparison with p63alpha [1];
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MX M00761 V$P53DECAMER_Q2.
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DR TRANSPATH: MO000044175.
DR EMBL: AF075435;
DR EMBL: AF533892;
DR UniProtKB: O88898-3;
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RN [1]; RE0024981.
RX PUBMED: 10227294.
RA Yang A., Schweitzer R., Sun D., Kaghad M., Walker N., Bronson R. T., Tabin C., Sharpe A., Caput D., Crum C., McKeon F.
RT p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development.
RL Nature 398:714-718 (1999).
RN [2]; RE0050255.
RX PUBMED: 16861923.
RA Rossi M., De Simone M., Pollice A., Santoro R., La Mantia G., Guerrini L., Calabro V.
RT Itch/AIP4 associates with and promotes p63 protein degradation.
RL Cell Cycle 5:1816-1822 (2006).
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