AC T09547
XX
ID T09547
XX
DT 16.01.2006 (created); jma.
DT 22.07.2015 (updated); sla.
CO Copyright (C), QIAGEN.
XX
FA MEF-2C
XX
SY MEF-2C; MEF2C; myocyte-specific enhancer factor 2C.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G005285 Mef2c.
XX
CL C0014; MADS; 5.1.1.1.3.
XX
FF involved in the development of the anterior heart field [5];
XX
IN T16290 Ben; human, Homo sapiens.
IN T04216 FOXK1; mouse, Mus musculus.
IN T08522 HDAC4-isoform1; human, Homo sapiens.
IN T10027 MyoD; Mammalia.
IN T25732 Notch1-isoform1; mouse, Mus musculus.
IN T10542 p300; mouse, Mus musculus.
XX
MX M02025 V$MEF2C_Q4.
MX M00941 V$MEF2_Q6_01.
MX M07424 V$MEF2_Q6_03.
XX
BS R21317.
BS R31138.
BS R27159.
BS R27161.
BS R73290.
BS R62315.
BS R62316.
BS R42396.
BS R00244.
BS R03585.
BS R09465.
BS R26333.
BS R61303.
BS R58298.
BS R68227.
BS R32856.
BS R40062.
XX
DR TRANSPATH: MO000056814.
DR TRANSCOMPEL: C00649.
DR UniProtKB: Q8CFN5;
XX
RN [1]; RE0015210.
RX PUBMED: 10082551.
RA Wilson-Rawls J., Molkentin J. D., Black B. L., Olson E. N.
RT Activated notch inhibits myogenic activity of the MADS-Box transcription factor myocyte enhancer factor 2C
RL Mol. Cell. Biol. 19:2853-2862 (1999).
RN [2]; RE0035630.
RX PUBMED: 15831463.
RA Ma K., Chan J. K., Zhu G., Wu Z.
RT Myocyte enhancer factor 2 acetylation by p300 enhances its DNA binding activity, transcriptional activity, and myogenic differentiation.
RL Mol. Cell. Biol. 25:3575-3582 (2005).
RN [3]; RE0046850.
RX PUBMED: 12857748.
RA Polly P., Haddadi L. M., Issa L. L., Subramaniam N., Palmer S. J., Tay E. S., Hardeman E. C.
RT hMusTRD1alpha1 represses MEF2 activation of the troponin I slow enhancer
RL J. Biol. Chem. 278:36603-10 (2003).
RN [4]; RE0048095.
RX PUBMED: 15743821.
RA Micheli L., Leonardi L., Conti F., Buanne P., Canu N., Caruso M., Tirone F.
RT PC4 coactivates MyoD by relieving the histone deacetylase 4-mediated inhibition of myocyte enhancer factor 2C.
RL Mol. Cell. Biol. 25:2242-2259 (2005).
RN [5]; RE0048412.
RX PUBMED: 15890826.
RA Phan D., Rasmussen T. L., Nakagawa O., McAnally J., Gottlieb P. D., Tucker P. W., Richardson J. A., Bassel-Duby R., Olson E. N.
RT BOP, a regulator of right ventricular heart development, is a direct transcriptional target of MEF2C in the developing heart.
RL Development 132:2669-2678 (2005).
RN [6]; RE0051683.
RX PUBMED: 17003042.
RA Wang Y., Su B., Xia Z.
RT Brain-derived neurotrophic factor activates ERK5 in cortical neurons via a Rap1-MEKK2 signaling cascade.
RL J. Biol. Chem. 281:35965-35974 (2006).
XX
//