AC T09437
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ID T09437
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DT 10.10.2006 (created); tgo.
DT 28.01.2015 (updated); spk.
CO Copyright (C), QIAGEN.
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FA NF-kappaB1
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SY 243/NFA-kappaB; EBP-1; H2TF1; KBF1; NF-kappa-B-p105; NF-kappa-B1 p84/NF-kappa-B1 p98; NF-kappaB (p50); NF-kappaB1; p50.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006465 Nfkb1.
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CL C0020; Rel; 6.1.1.1.1.
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CP Mouse fibroblasts [6].
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IN T19185 GLEA2; mouse, Mus musculus.
IN T22536 Hsp70; mouse, Mus musculus.
IN T00971 IkappaB-beta; mouse, Mus musculus.
IN T01924 NF-kappaB1-isoform1; mouse, Mus musculus.
IN T19129 NF-kappaB2; mouse, Mus musculus.
IN T01427 p300; human, Homo sapiens.
IN T10542 p300; mouse, Mus musculus.
IN T09106 RelA-p65; mouse, Mus musculus.
IN T10397 RelA-p65; Mammalia.
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MX M08999 V$NFKB1_05.
MX M00194 V$NFKB_Q6.
MX M00774 V$NFKB_Q6_01.
MX M03557 V$P50_Q6.
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BS R20924.
BS R26286.
BS R22751.
BS R22752.
BS R18403.
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DR TRANSPATH: MO000088836.
DR UniProtKB: P25799;
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RN [1]; RE0030766.
RX PUBMED: 12482991.
RA Lang V., Janzen J., Fischer G. Z., Soneji Y., Beinke S., Salmeron A., Allen H., Hay R. T., Ben-Neriah Y., Ley S. C.
RT betaTrCP-mediated proteolysis of NF-kappaB1 p105 requires phosphorylation of p105 serines 927 and 932.
RL Mol. Cell. Biol. 23:402-13 (2003).
RN [2]; RE0030792.
RX PUBMED: 12352969.
RA Claudio E., Brown K., Park S., Wang H., Siebenlist U.
RT BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.
RL Nat. Immunol. 3:958-65 (2002).
RN [3]; RE0042226.
RX PUBMED: 12960163.
RA Hassa P. O., Buerki C., Lombardi C., Imhof R., Hottiger M. O.
RT Transcriptional coactivation of nuclear factor-kappaB-dependent gene expression by p300 is regulated by poly(ADP)-ribose polymerase-1
RL J. Biol. Chem. 278:45145-53 (2003).
RN [4]; RE0049582.
RX PUBMED: 16448710.
RA Babu G. R., Jin W., Norman L., Waterfield M., Chang M., Wu X., Zhang M., Sun S. C.
RT Phosphorylation of NF-kappaB1/p105 by oncoprotein kinase Tpl2: implications for a novel mechanism of Tpl2 regulation.
RL Biochim. Biophys. Acta 1763:174-181 (2006).
RN [5]; RE0051601.
RX PUBMED: 10516305.
RA Yu Z., Zhou D., Bruce-Keller A. J., Kindy M. S., Mattson M. P.
RT Lack of the p50 subunit of nuclear factor-kappaB increases the vulnerability of hippocampal neurons to excitotoxic injury.
RL J. Neurosci. 19:8856-8865 (1999).
RN [6]; RE0051710.
RX PUBMED: 15988009.
RA Yang H., Magilnick N., Lee C., Kalmaz D., Ou X., Chan J. Y., Lu S. C.
RT Nrf1 and Nrf2 regulate rat glutamate-cysteine ligase catalytic subunit transcription indirectly via NF-kappaB and AP-1.
RL Mol. Cell. Biol. 25:5933-5946 (2005).
RN [7]; RE0053748.
RX PUBMED: 12871932.
RA Demarchi F., Bertoli C., Sandy P., Schneider C.
RT Glycogen synthase kinase-3 beta regulates NF-kappa B1/p105 stability.
RL J. Biol. Chem. 278:39583-39590 (2003).
RN [8]; RE0054106.
RX PUBMED: 9314550.
RA Ishikawa H., Carrasco D., Claudio E., Ryseck R. P., Bravo R.
RT Gastric hyperplasia and increased proliferative responses of lymphocytes in mice lacking the COOH-terminal ankyrin domain of NF-kappaB2.
RL J. Exp. Med. 186:999-1014 (1997).
RN [9]; RE0065096.
RX PUBMED: 18180283.
RA Windheim M., Stafford M., Peggie M., Cohen P.
RT Interleukin-1 (IL-1) induces the Lys63-linked polyubiquitination of IL-1 receptor-associated kinase 1 to facilitate NEMO binding and the activation of IkappaBalpha kinase.
RL Mol. Cell. Biol. 28:1783-1791 (2008).
RN [10]; RE0065527.
RX PUBMED: 19531803.
RA Wall E. A., Zavzavadjian J. R., Chang M. S., Randhawa B., Zhu X., Hsueh R. C., Liu J., Driver A., Bao X. R., Sternweis P. C., Simon M. I., Fraser I. D.
RT Suppression of LPS-induced TNF-alpha production in macrophages by cAMP is mediated by PKA-AKAP95-p105.
RL Sci. Signal. 2:ra28 (2009).
RN [11]; RE0069256.
RX PUBMED: 18606643.
RA Hara H., Ishihara C., Takeuchi A., Xue L., Morris S. W., Penninger J. M., Yoshida H., Saito T.
RT Cell type-specific regulation of ITAM-mediated NF-kappaB activation by the adaptors, CARMA1 and CARD9.
RL J. Immunol. 181:918-930 (2008).
RN [12]; RE0069688.
RX PUBMED: 20716763.
RA Mieulet V., Yan L., Choisy C., Sully K., Procter J., Kouroumalis A., Krywawych S., Pende M., Ley S. C., Moinard C., Lamb R. F.
RT TPL-2-mediated activation of MAPK downstream of TLR4 signaling is coupled to arginine availability.
RL Sci. Signal. 3:ra61 (2010).
RN [13]; RE0071600.
RX PUBMED: 18436238.
RA Trinh D. V., Zhu N., Farhang G., Kim B. J., Huxford T.
RT The nuclear I kappaB protein I kappaB zeta specifically binds NF-kappaB p50 homodimers and forms a ternary complex on kappaB DNA.
RL J. Mol. Biol. 379:122-135 (2008).
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