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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T10718 XX ID T10718 XX DT 12.02.2006 (created); sbr. DT 06.11.2012 (updated); yre. CO Copyright (C), QIAGEN. XX FA RPA2 XX SY REPA2; replication protein A2, 32kDa; RP4-547C9.3; RPA2; RPA32. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G019421 RPA2; HGNC: RPA2. XX IN T02524 Grg-1; human, Homo sapiens. IN T34268 mcm3; human, Homo sapiens. IN T08321 p53-isoform1; human, Homo sapiens. IN T00671 p53; human, Homo sapiens. IN T10717 RPA1; human, Homo sapiens. IN T10719 RPA3; human, Homo sapiens. XX BS R21856. XX DR TRANSPATH: MO000065908. DR UniProtKB: P15927; RFA2_HUMAN. XX RN [1]; RE0005453. RX PUBMED: 8361542. RA Dutta A., Ruppert J. M., Aster J. C., Winchester E. RT Inhibition of DNA replication factor RPA by p53 RL Nature 365:79-82 (1993). RN [2]; RE0040810. RX PUBMED: 10625690. RA Liu J. S., Kuo S. R., McHugh M. M., Beerman T. A., Melendy T. RT Adozelesin triggers DNA damage response pathways and arrests SV40 DNA replication through replication protein A inactivation RL J. Biol. Chem. 275:1391-7 (2000). RN [3]; RE0047184. RX PUBMED: 15897895. RA Wu X., Shell S. M., Zou Y. RT Interaction and colocalization of Rad9/Rad1/Hus1 checkpoint complex with replication protein A in human cells RL Oncogene 24:4728-35 (2005). RN [4]; RE0047879. RX PUBMED: 9121469. RA Miller S. D., Moses K., Jayaraman L., Prives C. RT Complex formation between p53 and replication protein A inhibits the sequence-specific DNA binding of p53 and is regulated by single-stranded DNA. RL Mol. Cell. Biol. 17:2194-2201 (1997). RN [5]; RE0048117. RX PUBMED: 11092888. RA Parker A., Gu Y., Mahoney W., Lee S. H., Singh K. K., Lu A. L. RT Human homolog of the MutY repair protein (hMYH) physically interacts with proteins involved in long patch DNA base excision repair. RL J. Biol. Chem. 276:5547-5555 (2001). RN [6]; RE0063261. RX PUBMED: 16169070. RA Stelzl U., Worm U., Lalowski M., Haenig C., Brembeck F. H., Goehler H., Stroedicke M., Zenkner M., Schoenherr A., Koeppen S., Timm J., Mintzlaff S., Abraham C., Bock N., Kietzmann S., Goedde A., Toksoz E., Droege A., Krobitsch S., Korn B., Birchmeier W., Lehrach H., Wanker E. E. RT A human protein-protein interaction network: a resource for annotating the proteome. RL Cell 122:957-968 (2005). RN [7]; RE0063367. RX PUBMED: 19054765. RA Ballabeni A., Zamponi R., Caprara G., Melixetian M., Bossi S., Masiero L., Helin K. RT Human CDT1 associates with CDC7 and recruits CDC45 to chromatin during S phase. RL J. Biol. Chem. 284:3028-3036 (2009). RN [8]; RE0064397. RX PUBMED: 17715134. RA Lee A. Y., Liu E., Wu X. RT The Mre11/Rad50/Nbs1 complex plays an important role in the prevention of DNA rereplication in mammalian cells. RL J. Biol. Chem. 282:32243-32255 (2007). RN [9]; RE0065929. RX PUBMED: 20016603. RA Galanty Y., Belotserkovskaya R., Coates J., Polo S., Miller K. M., Jackson S. P. RT Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks. RL Nature 462:935-939 (2009). XX //