AC T10936
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ID T10936
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DT 15.06.2007 (created); lyn.
DT 23.10.2007 (updated); din.
CO Copyright (C), QIAGEN.
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FA Nrf2-isoform2
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SY NFE2L2; NRF2; nuclear factor (erythroid-derived 2)-like 2.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004136 NFE2L2; HGNC: NFE2L2.
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CL C0008; bZIP; 1.1.1.2.3.2.
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SZ 589 AA; 66.1 kDa (cDNA) (calc.).
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SQ MDLIDILWRQDIDLGVSREVFDFSQRRKEYELEKQKKLEKERQEQLQKEQEKAFFAQLQL
SQ DEETGEFLPIQPAQHIQSETSGSANYSQVAHIPKSDALYFDDCMQLLAQTFPFVDDNEVS
SQ SATFQSLVPDIPGHIESPVFIATNQAQSPETSVAQVAPVDLDGMQQDIEQVWEELLSIPE
SQ LQCLNIENDKLVETTMVPSPEAKLTEVDNYHFYSSIPSMEKEVGNCSPHFLNAFEDSFSS
SQ ILSTEDPNQLTVNSLNSDATVNTDFGDEFYSAFIAEPSISNSMPSPATLSHSLSELLNGP
SQ IDVSDLSLCKAFNQNHPESTAEFNDSDSGISLNTSPSVASPEHSVESSSYGDTLLGLSDS
SQ EVEELDSAPGSVKQNGPKTPVHSSGDMVQPLSPSQGQSTHVHDAQCENTPEKELPVSPGH
SQ RKTPFTKDKHSSRLEAHLTRDELRAKALHIPFPVEKIINLPVVDFNEMMSKEQFNEAQLA
SQ LIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLDHLKDEKEKLLKEKGENDKSLHLLKKQ
SQ LSTLYLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKSKKPDVKKN
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SC Swiss-Prot#Q16236-2
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FT 175 188 Nuclear Export Signal (NES) [2].
FT 536 547 Nuclear Export Signal (NES) [2].
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IN T02529 PPARgamma1; mouse, Mus musculus.
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MX M07296 V$MAF_Q4.
MX M00983 V$MAF_Q6_01.
MX M07610 V$NRF2_Q3.
MX M00821 V$NRF2_Q4.
MX M07265 V$NRF2_Q4_01.
MX M03835 V$NRF2_Q6.
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DR TRANSPATH: MO000108712.
DR UniProtKB: Q16236-2;
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RN [1]; RE0017304.
RX PUBMED: 10930400.
RA Ikeda Y., Sugawara A., Taniyama Y., Uruno A., Igarashi K., Arima S., Ito S., Takeuchi K.
RT Suppression of rat thromboxane synthase gene transcription by peroxisome proliferator-activated receptor gamma in macrophages via an interaction with NRF2
RL J. Biol. Chem. 275:33142-33150 (2000).
RN [2]; RE0051048.
RX PUBMED: 17636022.
RA Sun Z., Zhang S., Chan J. Y., Zhang D. D.
RT Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2.
RL Mol. Cell. Biol. 27:6334-6349 (2007).
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