AC T13786
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ID T13786
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DT 17.08.2007 (created); din.
DT 15.12.2007 (updated); pch.
CO Copyright (C), QIAGEN.
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FA KEAP1
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SY Cytosolic inhibitor of Nrf2; INrf2; KEAP1; kelch-like ECH-associated protein 1.
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G044541 Keap1.
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CP Normal liver cells and LEC liver (hepatocarcinogenesis) [2].
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IN T08469 Nrf2; mouse, Mus musculus.
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DR TRANSPATH: MO000112212.
DR UniProtKB: P57790; KEAP1_RAT.
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RN [1]; RE0050591.
RX PUBMED: 11439354.
RA Dhakshinamoorthy S., Jaiswal A. K.
RT Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene.
RL Oncogene 20:3906-3917 (2001).
RN [2]; RE0051283.
RX PUBMED: 14960151.
RA Ikeda H., Nishi S., Sakai M.
RT Transcription factor Nrf2/MafK regulates rat placental glutathione S-transferase gene during hepatocarcinogenesis.
RL Biochem. J. 380:515-521 (2004).
RN [3]; RE0051375.
RX PUBMED: 14673141.
RA Itoh K., Mochizuki M., Ishii Y., Ishii T., Shibata T., Kawamoto Y., Kelly V., Sekizawa K., Uchida K., Yamamoto M.
RT Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12,14)-prostaglandin j(2).
RL Mol. Cell. Biol. 24:36-45 (2004).
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