AC T14062
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ID T14062
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DT 10.03.2005 (created); nvo.
DT 02.03.2016 (updated); vis.
CO Copyright (C), QIAGEN.
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FA Elk-1
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SY ELK1, member of ETS oncogene family.
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OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
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IN T15204 brca1; Mammalia.
IN T15118 CBP; Mammalia.
IN T14063 SRF; Mammalia.
XX
MX M00007 V$ELK1_01.
MX M00025 V$ELK1_02.
MX M01163 V$ELK1_03.
MX M01165 V$ELK1_04.
MX M07252 V$ELK1_Q4.
MX M03819 V$ELK1_Q6.
MX M00771 V$ETS_Q4.
MX M00971 V$ETS_Q6.
XX
BS R72225.
BS R00462.
BS R72958.
BS R01711.
BS R23149.
BS R60611.
BS R71258.
XX
DR TRANSPATH: MO000046899.
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RN [1]; RE0005335.
RX PUBMED: 8477450.
RA Hill C. S., Marais R., John S., Wynne J., Dalton S., Treisman R.
RT Functional analysis of a growth factor-responsive transcription factor complex
RL Cell 73:395-406 (1993).
RN [2]; RE0016596.
RX PUBMED: 8083220.
RA Latinkic B. V., Lau L. F.
RT Transcription activation of the immediate early gene pip92 by serum growth factors requires both Ets and CArG-like elements.
RL J. Biol. Chem. 269:23163-23170 (1994).
RN [3]; RE0020975.
RX PUBMED: 9029150.
RA Cuenda A., Cohen P., Buee-Scherrer V., Goedert M.
RT Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38)
RL EMBO J. 16:295-305 (1997).
RN [4]; RE0027197.
RX PUBMED: 11032810.
RA Zhang B. H., Guan K. L.
RT Activation of B-Raf kinase requires phosphorylation of the conserved residues thr598 and ser601
RL EMBO J. 19:5429-39 (2000).
RN [5]; RE0028344.
RX PUBMED: 11083868.
RA Nissen L. J., Gelly J. C., Hipskind R. A.
RT Induction-independent recruitment of CREB-binding protein to the c-fos serum response element through interactions between the bromodomain and Elk-1.
RL J. Biol. Chem. 276:5213-21 (2001).
RN [6]; RE0028861.
RX PUBMED: 10191264.
RA Chang M. S., Yoo H. Y., Rho H. M.
RT Positive and negative regulatory elements in the upstream region of the rat Cu/Zn-superoxide dismutase gene.
RL Biochem. J. 339:335-41 (1999).
RN [7]; RE0029861.
RX PUBMED: 12239223.
RA Guo Y. S., Cheng J. Z., Jin G. F., Gutkind J. S., Hellmich M. R., Townsend C. M. Jr.
RT Gastrin stimulates cyclooxygenase-2 expression in intestinal epithelial cells through multiple signaling pathways. Evidence for involvement of ERK5 kinase and transactivation of the epidermal growth factor receptor.
RL J. Biol. Chem. 277:48755-63 (2002).
RN [8]; RE0033960.
RX PUBMED: 15078890.
RA Nishihara H., Hwang M., Kizaka-Kondoh S., Eckmann L., Insel P. A.
RT Cyclic AMP promotes cAMP-responsive element-binding protein-dependent induction of cellular inhibitor of apoptosis protein-2 and suppresses apoptosis of colon cancer cells through ERK1/2 and p38 MAPK.
RL J. Biol. Chem. 279:26176-83 (2004).
RN [9]; RE0034783.
RX PUBMED: 11279280.
RA Iwata A., Miura S., Kanazawa I., Sawada M., Nukina N.
RT alpha-Synuclein forms a complex with transcription factor Elk-1.
RL J. Neurochem 77:239-52 (2001).
RN [10]; RE0034924.
RX PUBMED: 10400627.
RA Hashimoto A., Kurosaki M., Gotoh N., Shibuya M., Kurosaki T.
RT Shc regulates epidermal growth factor-induced activation of the JNK signaling pathway.
RL J. Biol. Chem. 274:20139-43 (1999).
RN [11]; RE0036810.
RX PUBMED: 12874243.
RA Jensen L. E., Whitehead A. S.
RT Pellino3, a novel member of the Pellino protein family, promotes activation of c-Jun and Elk-1 and may act as a scaffolding protein
RL J. Immunol. 171:1500-6 (2003).
RN [12]; RE0037508.
RX PUBMED: 11934987.
RA Stevens J. L., Cantin G. T., Wang G., Shevchenko A., Shevchenko A., Berk A. J.
RT Transcription control by E1A and MAP kinase pathway via Sur2 mediator subunit
RL Science 296:755-8 (2002).
RN [13]; RE0037694.
RX PUBMED: 14602719.
RA Zagar Y., Chaumaz G., Lieberherr M.
RT Signaling cross-talk from Gbeta4 subunit to Elk-1 in the rapid action of androgens
RL J. Biol. Chem. 279:2403-13 (2004).
RN [14]; RE0038790.
RX PUBMED: 9832424.
RA Kim B., Leventhal P. S., White M. F., Feldman E. L.
RT Differential regulation of insulin receptor substrate-2 and mitogen-activated protein kinase tyrosine phosphorylation by phosphatidylinositol 3-kinase inhibitors in SH-SY5Y human neuroblastoma cells.
RL Endocrinology 139:4881-4889 (1998).
RN [15]; RE0039591.
RX PUBMED: 10799319.
RA Huang Y., Deng T., Winston B. W.
RT Characterization of hPRP4 kinase activation: potential role in signaling
RL Biochem. Biophys. Res. Commun. 271:456-63 (2000).
RN [16]; RE0043426.
RX PUBMED: 15258260.
RA Tung E. K., Choi R. C., Siow N. L., Jiang J. X., Ling K. K., Simon J., Barnard E. A., Tsim K. W.
RT P2Y2 receptor activation regulates the expression of acetylcholinesterase and acetylcholine receptor genes at vertebrate neuromuscular junctions
RL Mol. Pharmacol. 66:794-806 (2004).
RN [17]; RE0043518.
RX PUBMED: 11799073.
RA Hattori Y., Suzuki M., Hattori S., Kasai K.
RT Vascular smooth muscle cell activation by glycated albumin (Amadori adducts)
RL Hypertension 39:22-8 (2002).
RN [18]; RE0043955.
RX PUBMED: 10903733.
RA Hatzoglou A., Roussel J., Bourgeade M. F., Rogier E., Madry C., Inoue J., Devergne O., Tsapis A.
RT TNF receptor family member BCMA (B cell maturation) associates with TNF receptor-associated factor (TRAF) 1, TRAF2, and TRAF3 and activates NF-kappa B, elk-1, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase
RL J. Immunol. 165:1322-30 (2000).
RN [19]; RE0047561.
RX PUBMED: 15655247.
RA Bourguignon L. Y., Gilad E., Rothman K., Peyrollier K.
RT Hyaluronan-CD44 interaction with IQGAP1 promotes Cdc42 and ERK signaling, leading to actin binding, Elk-1/estrogen receptor transcriptional activation, and ovarian cancer progression.
RL J. Biol. Chem. 280:11961-11972 (2005).
RN [20]; RE0053743.
RX PUBMED: 18083124.
RA Li A. Y., Han M., Zheng B., Wen J. K.
RT Roscovitine inhibits ERK1/2 activation induced by angiotensin II in vascular smooth muscle cells.
RL FEBS Lett. 582:243-248 (2008).
RN [21]; RE0053849.
RX PUBMED: 16822942.
RA Xu S., Bayat H., Hou X., Jiang B.
RT Ribosomal S6 kinase-1 modulates interleukin-1beta-induced persistent activation of NF-kappaB through phosphorylation of IkappaBbeta.
RL Am. J. Physiol. Cell Physiol. 291:C1336-45 (2006).
RN [22]; RE0054543.
RX PUBMED: 17317104.
RA Jamaluddin M., Wang S., Boldogh I., Tian B., Brasier A. R.
RT TNF-alpha-induced NF-kappaB/RelA Ser(276) phosphorylation and enhanceosome formation is mediated by an ROS-dependent PKAc pathway.
RL Cell. Signal. 19:1419-1433 (2007).
RN [23]; RE0054772.
RX PUBMED: 17689131.
RA Humar M., Loop T., Schmidt R., Hoetzel A., Roesslein M., Andriopoulos N., Pahl H. L., Geiger K. K., Pannen B. H.
RT The mitogen-activated protein kinase p38 regulates activator protein 1 by direct phosphorylation of c-Jun.
RL Int. J. Biochem. Cell Biol. 39:2278-2288 (2007).
RN [24]; RE0062979.
RX PUBMED: 15537652.
RA He Z., Cho Y. Y., Ma W. Y., Choi H. S., Bode A. M., Dong Z.
RT Regulation of ultraviolet B-induced phosphorylation of histone H3 at serine 10 by Fyn kinase.
RL J. Biol. Chem. 280:2446-2454 (2005).
RN [25]; RE0063960.
RX PUBMED: 18556463.
RA Madonna S., Scarponi C., De Pita O., Albanesi C.
RT Suppressor of cytokine signaling 1 inhibits IFN-gamma inflammatory signaling in human keratinocytes by sustaining ERK1/2 activation.
RL FASEB J. 22:3287-3297 (2008).
RN [26]; RE0066259.
RX PUBMED: 15280429.
RA Manohar A., Shome S. G., Lamar J., Stirling L., Iyer V., Pumiglia K., DiPersio C. M.
RT Alpha 3 beta 1 integrin promotes keratinocyte cell survival through activation of a MEK/ERK signaling pathway.
RL J. Cell Sci. 117:4043-4054 (2004).
RN [27]; RE0067181.
RX PUBMED: 11313879.
RA Chai Y., Chipitsyna G., Cui J., Liao B., Liu S., Aysola K., Yezdani M., Reddy E. S., Rao V. N.
RT c-Fos oncogene regulator Elk-1 interacts with BRCA1 splice variants BRCA1a/1b and enhances BRCA1a/1b-mediated growth suppression in breast cancer cells.
RL Oncogene 20:1357-1367 (2001).
RN [28]; RE0067621.
RX PUBMED: 16291755.
RA Eliopoulos A. G., Das S., Tsichlis P. N.
RT The tyrosine kinase Syk regulates TPL2 activation signals.
RL J. Biol. Chem. 281:1371-1380 (2006).
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