TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T14816 XX ID T14816 XX DT 10.03.2005 (created); nvo. DT 21.08.2015 (updated); jmh. CO Copyright (C), QIAGEN. XX FA IRF-1 XX SY Interferon regulatory factor 1; IRF-1; IRF1; ISGF2. XX OS Mammalia OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia XX IN T11261 c-Rel; Mammalia. IN T10358 HMGIY; Mammalia. IN T10639 HMGIY; Mammalia. IN T14446 IRF-2; Mammalia. IN T30703 SIRT1; Mammalia. IN T00818 TFIIB; human, Homo sapiens. XX MX M00062 V$IRF1_01. MX M07045 V$IRF1_Q5. MX M00747 V$IRF1_Q6. MX M08887 V$IRF_Q4. MX M00772 V$IRF_Q6. MX M00972 V$IRF_Q6_01. XX BS R26813. BS R56000. BS R27021. BS R73900. BS R56783. BS R00919. BS R26805. BS R26810. BS R26812. BS R58177. BS R25033. BS R68651. BS R74073. BS R68657. BS R69335. XX DR TRANSPATH: MO000046773. DR TRANSCOMPEL: C00060. DR TRANSCOMPEL: C00061. DR TRANSCOMPEL: C00337. DR TRANSCOMPEL: C00601. XX RN [1]; RE0007708. RX PUBMED: 7686487. RA Parrington J., Rogers N. C., Gewert D. R., Pine R., Veals S. A., Levy D. E., Stark G. R., Kerr I. M. RT The interferon-stimulable response elements of two human genes detect overlapping sets of transcription factors RL Eur. J. Biochem. 214:617-626 (1993). RN [2]; RE0017773. RX PUBMED: 11303025. RA Barnes B. J., Moore P. A., Pitha P. M. RT Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes. RL J. Biol. Chem. 276:23382-23390 (2001). RN [3]; RE0018012. RX PUBMED: 8887661. RA Wang I. M., Blanco J. C., Tsai S. Y., Tsai M. J., Ozato K. RT Interferon regulatory factors and TFIIB cooperatively regulate interferon-responsive promoter activity in vivo and in vitro. RL Mol. Cell. Biol. 16:6313-6324 (1996). RN [4]; RE0024011. RX PUBMED: 10357819. RA Yie J., Merika M., Munshi N., Chen G., Thanos D. RT The role of HMG I(Y) in the assembly and function of the IFN-beta enhanceosome. RL EMBO J. 18:3074-3089 (1999). RN [5]; RE0029652. RX PUBMED: 9195941. RA Ossina N. K., Cannas A., Powers V. C., Fitzpatrick P. A., Knight J. D., Gilbert J. R., Shekhtman E. M., Tomei L. D., Umansky S. R., Kiefer M. C. RT Interferon-gamma modulates a p53-independent apoptotic pathway and apoptosis-related gene expression. RL J. Biol. Chem. 272:16351-7 (1997). RN [6]; RE0032245. RX PUBMED: 11147573. RA Baron-Delage S., Abadie A., Echaniz-Laguna A., Melki J., Beretta L. RT Interferons and IRF-1 induce expression of the survival motor neuron (SMN) genes. RL Mol. Med. 6:957-68 (2000). RN [7]; RE0037671. RX PUBMED: 10930443. RA Kelley T. J., Elmer H. L. RT In vivo alterations of IFN regulatory factor-1 and PIAS1 protein levels in cystic fibrosis epithelium RL J. Clin. Invest. 106:403-10 (2000). RN [8]; RE0038950. RX PUBMED: 11694524. RA Blair L. A., Maggi L. B. Jr, Scarim A. L., Corbett J. A. RT Role of interferon regulatory factor-1 in double-stranded RNA-induced iNOS expression by mouse islets RL J. Biol. Chem. 277:359-65 (2002). RN [9]; RE0041927. RX PUBMED: 11342426. RA Fagerlie S. R., Diaz J., Christianson T. A., McCartan K., Keeble W., Faulkner G. R., Bagby G. C. RT Functional correction of FA-C cells with FANCC suppresses the expression of interferon gamma-inducible genes RL Blood 97:3017-24 (2001). RN [10]; RE0043253. RX PUBMED: 10446388. RA Tnani M., Bayard B. A. RT Evidence for IRF-1-dependent gene expression deficiency in interferon unresponsive HepG2 cells RL Biochim. Biophys. Acta 1451:59-72 (1999). RN [11]; RE0044781. RX PUBMED: 10227981. RA Ackermann L. W., Wollenweber L. A., Denning G. M. RT IL-4 and IFN-gamma increase steady state levels of polymeric Ig receptor mRNA in human airway and intestinal epithelial cells RL J. Immunol. 162:5112-8 (1999). RN [12]; RE0046834. RX PUBMED: 11781233. RA Wagner A. H., Gebauer M., Pollok-Kopp B., Hecker M. RT Cytokine-inducible CD40 expression in human endothelial cells is mediated by interferon regulatory factor-1 RL Blood 99:520-5 (2002). RN [13]; RE0053348. RX PUBMED: 17018642. RA Negishi H., Fujita Y., Yanai H., Sakaguchi S., Ouyang X., Shinohara M., Takayanagi H., Ohba Y., Taniguchi T., Honda K. RT Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program. RL Proc. Natl. Acad. Sci. USA 103:15136-15141 (2006). RN [14]; RE0064770. RX PUBMED: 18802049. RA Vila-del Sol V., Punzon C., Fresno M. RT IFN-gamma-induced TNF-alpha expression is regulated by interferon regulatory factors 1 and 8 in mouse macrophages. RL J. Immunol. 181:4461-4470 (2008). RN [15]; RE0065139. RX PUBMED: 17273999. RA Schmitz F., Heit A., Guggemoos S., Krug A., Mages J., Schiemann M., Adler H., Drexler I., Haas T., Lang R., Wagner H. RT Interferon-regulatory-factor 1 controls Toll-like receptor 9-mediated IFN-beta production in myeloid dendritic cells. RL Eur. J. Immunol. 37:315-327 (2007). RN [16]; RE0068264. RX PUBMED: 18955028. RA Kim E. J., Park J. S., Um S. J. RT Ubc9-mediated sumoylation leads to transcriptional repression of IRF-1. RL Biochem. Biophys. Res. Commun. 377:952-956 (2008). RN [17]; RE0068472. RX PUBMED: 10094406. RA Lin R., Hiscott J. RT A role for casein kinase II phosphorylation in the regulation of IRF-1 transcriptional activity. RL Mol. Cell. Biochem. 191:169-180 (1999). XX //