AC T15516
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ID T15516
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DT 09.12.2008 (created); jag.
DT 14.06.2013 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA HNF-4gamma-isoform1
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SY hepatocyte nuclear factor 4gamma; HNF4G; NR2A2.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004700 HNF4G; HGNC: HNF4G.
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CL C0002; CC (rec); 2.1.3.2.2.1.
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SZ 408 AA; 45.9 kDa (cDNA) (calc.).
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SQ MNTTDNGVNCLCAICGDRATGKHYGASTCDGCKGFFRRSIRKSHIYSCRFSRQCVVDKDK
SQ RNQCRYCRLRKCFRAGMKKEAVQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVS
SQ SPGSSTDINVKKIASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGEHL
SQ LLGATKRSMIYKDILLLGNNYVIHRNSCEVEISRVANRVLDELVRPFQEIQIDDNEYACL
SQ KAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGRFGELLLLLPTLQSITW
SQ QMIEQIQFVKLFGMVKIDNLLQEMLLGGASNDGSHLHHPMHPHLSQDPLTGQTILLGPMS
SQ TLVHADQISTPETPLPSPPQGSGQEQYKIAANQASVISHQHLSKQKQL
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SC translated from EMBL #AF133504
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FT 9 80 
SM00399; c4gold.
FT 9 84 
PS51030; NUCLEAR_REC_DBD_2.
FT 10 85 
PF00105; Zinc finger, C4 type (two domains).
FT 77 87 
T box [3].
FT 78 337 
PF00478; IMP dehydrogenase / GMP reductase domai.
FT 89 95 
A box, PKA phosphorylation recognition site [3].
FT 141 299 
SM00430; holi.
FT 144 324 
PF00104; Ligand-binding domain of nuclear hormon.
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IN T00373 HNF-4alpha1; human, Homo sapiens.
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MX M00762 V$DR1_Q3.
MX M00764 V$HNF4DR1_Q3.
MX M00967 V$HNF4_Q6.
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BS R04454.
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DR TRANSPATH: MO000150457.
DR EMBL: AF133504; AF133504.
DR EMBL: Z49826;
DR UniProtKB: Q14541-1;
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RN [1]; RE0006831.
RX PUBMED: 8622695.
RA Drewes T., Senkel S., Holewa B., Ryffel G. U.
RT Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes
RL Mol. Cell. Biol. 16:925-931 (1996).
RN [2]; RE0013625.
RX PUBMED: 10219237.
RA Nuclear Receptors Nomenclature Committee.
RT A unified nomenclature system for the nuclear receptor superfamily
RL Cell 97:161-163 (1999).
RN [3]; RE0018065.
RX PUBMED: 9234678.
RA Viollet B., Kahn A., Raymondjean M.
RT Protein kinase A-dependent phosphorylation modulates DNA-binding activity of hepatocyte nuclear factor 4.
RL Mol. Cell. Biol. 17:4208-4219 (1997).
RN [4]; RE0024855.
RX PUBMED: 10512380.
RA Plengvidhya N., Antonellis A., Wogan L. T., Poleev A., Borgschulze M., Warram J. H., Ryffel G. U., Krolewski A. S., Doria A.
RT Hepatocyte nuclear factor-4gamma: cDNA sequence, gene organization, and mutation screening in early-onset autosomal-dominant type 2 diabetes.
RL Diabetes 48:2099-2102 (1999).
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