AC T19112
XX
ID T19112
XX
DT 22.04.2006 (created); man.
DT 08.03.2012 (updated); mkl.
CO Copyright (C), QIAGEN.
XX
FA SMRT-xbb2
XX
SY CTG repeat protein 26; CTG26; N-COR2; NCOR2; nuclear receptor co-repressor 2; Nuclear receptor corepressor 2; Silencing mediator of retinoic acid and thyroid hormone receptor; SMAP270; SMRT; SMRTE; T3 receptor-associating factor; Thyroid-, retinoic-acid-receptor-associated corepressor; TNRC14; TRAC; TRAC-1; TRAC1.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G002795 NCOR2; HGNC: NCOR2.
XX
CL C0022; trp.
XX
SZ 1495 AA; 159.5 kDa (cDNA) (calc.).
XX
SQ MEAWDAHPDKEAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGH
SQ PLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHAK
SQ APVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPPESLGVPTAQEASVLRGTALGS
SQ VPGGSITKGIPSTRVPSDSAITYRGSITHGTPADVLYKGTITRIIGEDSPSRLDRGREDS
SQ LPKGHVIYEGKKGHVLSYEGGMSVTQCSKEDGRSSSGPPHETAAPKRTYDMMEGRVGRAI
SQ SSASIEGLMGRAIPPERHSPHHLKEQHHIRGSITQGIPRSYVEAQEDYLRREAKLLKREG
SQ TPPPPPPSRDLTEAYKTQALGPLKLKPAHEGLVATVKEAGRSIHEIPREELRHTPELPLA
SQ PRPLKEGSITQGTPLKYDTGASTTGSKKHDVRSLIGSPGRTFPPVHPLDVMADARALERA
SQ CYEESLKSRPGTASSSGGSIARGAPVIVPELGKPRQSPLTYEDHGAPFAGHLPRGSPVTM
SQ REPTPRLQEGSLSSSKASQDRKLTSTPREIAKSPHSTVPEHHPHPISPYEHLLRGVSGVD
SQ LYRSHIPLAFDPTSIPRGIPLDAAAAYYLPRHLAPNPTYPHLYPPYLIRGYPDTAALENR
SQ QTIINDYITSQQMHHNTATAMAQRADMLRGLSPRESSLALNYAAGPRGIIDLSQVPHLPV
SQ LVPPTPGTPATAMDRLAYLPTAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDR
SQ ERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPASHSHAHQHSP
SQ ISPRTQDALQQRPSVLHNTGMKGIITAVEPSKPTVLRSTSTSSPVRPAATFPPATHCPLG
SQ GTLDGVYPTLMEPVLLPKEAPRVARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPR
SQ PLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFSIQELELRSLG
SQ YHGSSYSPEGVEPVSPVSSPSLTHDKGLPKHLEELDKSHLEGELRPKQPGPVKLGGEAAH
SQ LPHLRPLPESQPSSSPLLQTAPGVKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAP
SQ LYSFPGASCPVLDLRRPPSDLYLPPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGI
SQ EPVSPPEGMTEPGHSRSAVYPLLYRDGEQTEPSRMGSKSPGNTSQPPAFFSKLTESNSAM
SQ VKSKKQEINKKLNTHNRNEPEYNISQPGTEIFNMPAITGTGLMTYRSQAVQEHASTNMGL
SQ EAIIRKALMGKYDQWEESPPLSANAFNPLNASASLPAAMPITAADGRSDHTLTSPGGGGK
SQ AKVSGRPSSRKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWEDRPSSAGSTPF
SQ PYNPLIMRLQAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYETLSDSE
XX
SC translated from EMBL:U37146
XX
IN T00545 POU2F1; human, Homo sapiens.
IN T08628 POU2F1; Mammalia.
IN T16056 RBPJK; Mammalia.
IN T08728 SKIP; human, Homo sapiens.
IN T08501 T3R-alpha; chick, Gallus gallus.
XX
DR TRANSPATH: MO000080460.
DR EMBL: U37146; U37146.
DR UniProtKB: Q9Y618;
XX
RN [1]; RE0045269.
RX PUBMED: 11509665.
RA Zhou S., Hayward S. D.
RT Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complex
RL Mol. Cell. Biol. 21:6222-32 (2001).
RN [2]; RE0045619.
RX PUBMED: 9405624.
RA Zamir I., Dawson J., Lavinsky R. M., Glass C. K., Rosenfeld M. G., Lazar M. A.
RT Cloning and characterization of a corepressor and potential component of the nuclear hormone receptor repression complex
RL Proc. Natl. Acad. Sci. USA 94:14400-5 (1997).
RN [3]; RE0047692.
RX PUBMED: 12805224.
RA Mendez-Pertuz M., Sanchez-Pacheco A., Aranda A.
RT The thyroid hormone receptor antagonizes CREB-mediated transcription.
RL EMBO J. 22:3102-3112 (2003).
RN [4]; RE0047947.
RX PUBMED: 11134019.
RA Kakizawa T., Miyamoto T., Ichikawa K., Takeda T., Suzuki S., Mori J., Kumagai M., Yamashita K., Hashizume K.
RT Silencing mediator for retinoid and thyroid hormone receptors interacts with octamer transcription factor-1 and acts as a transcriptional repressor.
RL J. Biol. Chem. 276:9720-9725 (2001).
XX
//