AC T22036
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ID T22036
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DT 30.05.2011 (created); grs.
DT 12.09.2014 (updated); sup.
CO Copyright (C), QIAGEN.
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FA DEC1
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SY basic helix-loop-helix domain containing, class B2; BHLHB2; C130042M06Rik; Clast5; CR8; DEC1; stimulated with RA 13; Stra13; Stra14.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G005824 Bhlhe40.
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CL C0010; bHLH.
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SZ 411 AA; 45.4 kDa (cDNA) (calc.).
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SQ MERIPSAQPPPTCLPKAPGLEHGDLSGMDFAHMYQVYKSRRGIKRSEDSKETYKLPHRLI
SQ EKKRRDRINECIAQLKDLLPEHLKLTTLGHLEKAVVLELTLKHVKALTNLIDQQQQKIIA
SQ LQSGLQAGDLSGRNLEAGQEMFCSGFQTCAREVLQYLAKHENTRDLKSSQLVTHLHRVVS
SQ ELLQGGASRKPLDSAPKAVDLKEKPSFLAKGSEGPGKNCVPVIQRTFAPSGGEQSGSDTD
SQ TDSGYGGELEKGDLRSEQPYFKSDHGRRFAVGERVSTIKQESEEPPTKKSRMQLSEEEGH
SQ FAGSDLMGSPFLGPHPHQPPFCLPFYLIPPSATAYLPMLEKCWYPTSVPVLYPGLNTSAA
SQ ALSSFMNPDKIPTPLLLPQRLPSPLAHSSLDSSALLQALKQIPPLNLETKD
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SC translated from EMBL #AF010305
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FT 44 108 PS50888; HLH.
FT 51 300 PF00478; IMP dehydrogenase / GMP reductase domain.
FT 53 108 PF00010; Helix-loop-helix DNA-binding domain.
FT 58 113 SM00353; finulus.
FT 140 184 PF07527; Hairy Orange.
FT 140 184 SM00511; ORANGE.
FT 142 175 PS51054; ORANGE.
FT 235 243 potential casein kinase II motif [1].
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IN T21852 HDAC1; Mammalia.
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MX M02845 V$BHLHB2_04.
MX M03572 V$DEC1_Q2.
MX M08870 V$DEC1_Q3.
MX M00997 V$DEC_Q1.
MX M08872 V$DEC_Q3.
MX M01034 V$EBOX_Q6_01.
MX M08885 V$HAIRYLIKE_Q3.
MX M00985 V$STRA13_01.
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BS R14580.
BS R14581.
BS R14582.
BS R14583.
BS R14584.
BS R14585.
BS R14586.
BS R14587.
BS R14588.
BS R14589.
BS R14590.
BS R14591.
BS R14592.
BS R14593.
BS R14594.
BS R14595.
BS R14596.
BS R14597.
BS R14598.
BS R14599.
BS R14600.
BS R14601.
BS R14602.
BS R32773.
BS R32737.
BS R32739.
BS R14604.
BS R63914.
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DR TRANSPATH: MO000180063.
DR EMBL: AF010305;
DR UniProtKB: O35185; BHB2_MOUSE.
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RN [1]; RE0005874.
RX PUBMED: 9284045.
RA Boudjelal M., Taneja R., Matsubara S., Bouillet P., Dolle P., Chambon P.
RT Overexpression of Stra13, a novel retinoic acid-inducible gene of the basic helix-loop-helix family, inhibits mesodermal and promotes neuronal differentiation of P19 cells
RL Genes Dev. 11:2052-2065 (1997).
RN [2]; RE0023863.
RX PUBMED: 12297495.
RA St-Pierre B., Flock G., Zacksenhaus E., Egan S. E.
RT Stra13 homodimers repress transcription through class B E-box elements.
RL J. Biol. Chem. 277:46544-46551 (2002).
RN [3]; RE0023876.
RX PUBMED: 12397359.
RA Honma S., Kawamoto T., Takagi Y., Fujimoto K., Sato F., Noshiro M., Kato Y., Honma K.
RT Dec1 and Dec2 are regulators of the mammalian molecular clock.
RL Nature 419:841-844 (2002).
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