AC T22504
XX
ID T22504
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DT 30.11.2009 (created); grs.
DT 21.04.2011 (updated); pos.
CO Copyright (C), QIAGEN.
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FA IkappaBzeta-isoform2
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SY FLJ30225; FLJ34463; I-kappa-B-zeta; IkappaBzeta; IkB-zeta; IKBZ; IL-1 inducible nuclear ankyrin-repeat protein; INAP; Mail; MAIL-S; Molecule possessing ankyrin repeats induced by lipopolysaccharide; NF-kappa-B inhibitor zeta; NFKBIZ; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta; Transcription variant 3.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G034821 NFKBIZ; HGNC: NFKBIZ.
XX
CL C0020; Rel; 6.1.2.1.5.2.
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SZ 618 AA; 68.2 kDa (calc.).
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SQ MGVGRQQRGPFQGVRVKNSVKELLLHIRSHKQKASGQAVDDFKTQGVNIEQFRELKNTVS
SQ YSGKRKGPDSLSDGPACKRPALLHSQFLTPPQTPTPGESMEDVHLNEPKQESSADLLQNI
SQ INIKNECSPVSLNTVQVSWLNPVVVPQSSPAEQCQDFHGGQVFSPPQKCQPFQVRGSQQM
SQ IDQASLYQYSPQNQHVEQQPHYTHKPTLEYSPFPIPPQSPAYEPNLFDGPESQFCPNQSL
SQ VSLLGDQRESENIANPMQTSSSVQQQNDAHLHSFSMMPSSACEAMVGHEMASDSSNTSLP
SQ FSNMGNPMNTTQLGKSLFQWQVEQEESKLANISQDQFLSKDADGDTFLHIAVAQGRRALS
SQ YVLARKMNALHMLDIKEHNGQSAFQVAVAANQHLIVQDLVNIGAQVNTTDCWGRTPLHVC
SQ AEKGHSQVLQAIQKGAVGSNQFVDLEATNYDGLTPLHCAVIAHNAVVHELQRNQQPHSPE
SQ VQELLLKNKSLVDTIKCLIQMGAAVEAKDRKSGRTALHLAAEEANLELIRLFLELPSCLS
SQ FVNAKAYNGNTALHVAASLQYRLTQLDAVRLLMRKGADPSTRNLENEQPVHLVPDGPVGE
SQ QIRRILKGKSIQQRAPPY
XX
SC Swiss-Prot#Q9BYH8-2
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IN T17520 NF-kappaB1; Mammalia.
IN T10397 RelA-p65; Mammalia.
XX
DR TRANSPATH: MO000165402.
DR UniProtKB: Q9BYH8-2; BZ_HUMAN.
XX
RN [1]; RE0069938.
RX PUBMED: 19783680.
RA Seshadri S., Kannan Y., Mitra S., Parker-Barnes J., Wewers M. D.
RT MAIL regulates human monocyte IL-6 production.
RL J. Immunol. 183:5358-5368 (2009).
RN [2]; RE0069949.
RX PUBMED: 16513645.
RA Totzke G., Essmann F., Pohlmann S., Lindenblatt C., Janicke R. U., Schulze-Osthoff K.
RT A novel member of the IkappaB family, human IkappaB-zeta, inhibits transactivation of p65 and its DNA binding.
RL J. Biol. Chem. 281:12645-12654 (2006).
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