AC T30113
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ID T30113
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DT 11.07.2001 (created); spi.
DT 28.01.2014 (updated); msr.
CO Copyright (C), QIAGEN.
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FA Trx1
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SY ADF; ATL-derived factor; SASP; thioredoxin 1; TRDX; TRX; Trx1; TXN.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G003640 TXN; HGNC: TXN.
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IN T29723 alpha-actinin-4; human, Homo sapiens.
IN T00337 GR-alpha; human, Homo sapiens.
IN T09484 NF-E2p45; human, Homo sapiens.
IN T34034 p21Cip1; human, Homo sapiens.
IN T08171 PSF; human, Homo sapiens.
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BS R59970.
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DR TRANSPATH: MO000021389.
DR UniProtKB: P10599;
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RN [1]; RE0025317.
RX PUBMED: 12208766.
RA Welsh S. J., Bellamy W. T., Briehl M. M., Powis G.
RT The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis.
RL Cancer Res. 62:5089-5095 (2002).
RN [2]; RE0054568.
RX PUBMED: 16263712.
RA Haendeler J., Popp R., Goy C., Tischler V., Zeiher A. M., Dimmeler S.
RT Cathepsin D and H2O2 stimulate degradation of thioredoxin-1: implication for endothelial cell apoptosis.
RL J. Biol. Chem. 280:42945-42951 (2005).
RN [3]; RE0067161.
RX PUBMED: 19805025.
RA Yoon K. W., Cho J. H., Lee J. K., Kang Y. H., Chae J. S., Kim Y. M., Kim J., Kim E. K., Kim S. E., Baik J. H., Naik U. P., Cho S. G., Choi E. J.
RT CIB1 functions as a Ca(2+)-sensitive modulator of stress-induced signaling by targeting ASK1.
RL Proc. Natl. Acad. Sci. USA 106:17389-17394 (2009).
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