AC T31792
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ID T31792
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DT 15.04.2002 (created); cch.
DT 17.02.2015 (updated); asv.
CO Copyright (C), QIAGEN.
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FA p53{pS20}
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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FF p53 is phosphorylated on Ser20 in response to UV and gamma radiation [4];
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IN T01318 CBP; mouse, Mus musculus.
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BS R66303.
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DR TRANSPATH: MO000030996.
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RN [1]; RE0020896.
RX PUBMED: 10432310.
RA Craig A. L., Burch L., Vojtesek B., Mikutowska J., Thompson A., Hupp T. R.
RT Novel phosphorylation sites of human tumour suppressor protein p53 at Ser20 and Thr18 that disrupt the binding of mdm2 (mouse double minute 2) protein are modified in human cancers
RL Biochem. J. 342:133-141 (1999).
RN [2]; RE0020918.
RX PUBMED: 11875057.
RA Saito S., Goodarzi A. A., Higashimoto Y., Noda Y., Lees-Miller S. P., Appella E., Anderson C. W.
RT ATM Mediates Phosphorylation at Multiple p53 Sites, Including Ser46, in Response to Ionizing Radiation
RL J. Biol. Chem. 277:12491-12494 (2002).
RN [3]; RE0020930.
RX PUBMED: 11447225.
RA Xie S., Wang Q., Wu H., Cogswell J., Lu L., Jhanwar-Uniyal M., Dai W.
RT Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3
RL J. Biol. Chem. 276:36194-36199 (2001).
RN [4]; RE0020946.
RX PUBMED: 11850826.
RA Miyakoda M., Suzuki K., Kodama S., Watanabe M.
RT Activation of ATM and phosphorylation of p53 by heat shock
RL Oncogene 21:1090-1096 (2002).
RN [5]; RE0049448.
RX PUBMED: 12381304.
RA Schon O., Friedler A., Bycroft M., Freund S. M., Fersht A. R.
RT Molecular mechanism of the interaction between MDM2 and p53.
RL J. Mol. Biol. 323:491-501 (2002).
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