AC T00117
XX
ID T00117
XX
DT 07.11.1992 (created); ewi.
DT 07.02.2006 (updated); vma.
CO Copyright (C), QIAGEN.
XX
FA CF1
XX
SY CF1; chorion factor 1; NR2B4; Ultraspiracle; USP; XR2C.
XX
OS fruit fly, Drosophila melanogaster
OC eukaryota; animalia; metazoa; arthropoda; insecta; diptera; drosophiloidea; drosophilidae
XX
GE G021778 usp.
XX
HO RXR-subfamiliy (vertebrate).
XX
CL C0002; CC (rec).
XX
SZ 508 AA; 55.2 kDa (cDNA) (calc.).
XX
SQ MDNCDQDASFRLSHIKEEVKPDISQLNDSNNSSFSPKAESPVPFMQAMSMVHVLPGSNSA
SQ SSNNNSAGDAQMAQAPNSAGGSAAAAVQQQYPPNHPLSGSKHLCSICGDRASGKHYGVYS
SQ CEGCKGFFKRTVRKDLTYACRENRNCIIDKRQRNRCQYCRYQKCLTCGMKREAVQEERQR
SQ GARNAAGRLSASGGGSSGPGSVGGSSSQGGGGGGGVSGGMGSGNGSDDFMTNSVSRDFSI
SQ ERIIEAEQRAETQCGDRALTFLRVGPYSTVQPDYKGAVSALCQVVNKQLFQMVEYARMMP
SQ HFAQVPLDDQVILLKAAWIELLIANVAWCSIVSLDDGGAGGGGGGLGHDGSFERRSPGLQ
SQ PQQLFLNQSFSYHRNSAIKAGVSAIFDRILSELSVKMKRLNLDRRELSCLKAIILYNPDI
SQ RGIKSRAEIEMCREKVYACLDEHCRLEHPGDDGRFAQLLLRLPALRSISLKCQDHLFLFR
SQ ITSDRPLEELFLEQLEAPPPPGLAMKLE
XX
SC Swiss-Prot#P20153
XX
FT 1 103 
region A/B (transactivation function) [3].
FT 25 312 
PF00478; IMP dehydrogenase / GMP reductase domai.
FT 101 172 
SM00399; c4gold.
FT 101 176 
PS51030; NUCLEAR_REC_DBD_2.
FT 102 177 
PF00105; Zinc finger, C4 type (two domains).
FT 104 169 
region C (DNA-binding, dimerization) [3].
FT 169 223 
region D (hinge region) [3].
FT 224 508 
region E (ligand-binding, dimerization) [3].
FT 283 469 
SM00430; holi.
FT 286 494 
PF00104; Ligand-binding domain of nuclear hormon.
XX
CP enriched in follicles.
XX
FF maternally and zygotically expressed gene with multiple functions in development: required in the eye-antennal imaginal disc for normal eye morphogenesis, in the somatic and germline tissues of adult females for fertilization, eggshell morphogenesis and embryonic development [6];
FF functions via cell autonomous and non-cell autonomous components, what was leading to speculation that it is responsible for directing synthesis of factors important for cell-cell communication as well as cellular differentiation [6];
XX
IN T00217 EcR; fruit fly, Drosophila melanogaster.
IN T00841 T3R-alpha; rat, Rattus norvegicus.
XX
MX M00111 I$CF1_01.
MX M00112 I$CF1_02.
XX
BS R10931.
BS R10932.
BS R10933.
BS R10934.
BS R10935.
BS R10936.
BS R10937.
BS R10938.
BS R10939.
BS R10940.
BS R10941.
BS R10942.
BS R10943.
BS R10944.
BS R10945.
BS R10946.
BS R10947.
BS R10948.
BS R10949.
BS R10950.
BS R10951.
BS R10952.
BS R10953.
BS R10954.
BS R10955.
BS R10956.
BS R10957.
BS R10958.
BS R10959.
BS R10960.
BS R10961.
BS R10962.
BS R10963.
BS R10964.
BS R10965.
BS R10966.
BS R10967.
BS R10968.
BS R03988.
BS R04611.
BS R02294.
XX
DR TRANSPATH: MO000024718.
DR EMBL: X52591;
DR EMBL: X53417;
DR UniProtKB: P20153;
DR FLYBASE: FBgn0003964; usp.
XX
RN [1]; RE0000756.
RX PUBMED: 2120114.
RA Shea M. J., King D. L., Conboy M. J., Mariani B. D., Kafatos F. C.
RT Proteins that bind to Drosophila chorion cis-regulatory elements: A new C2H2 zinc finger protein and a C2C2 steroid receptor-like component
RL Genes Dev. 4:1128-1140 (1990).
RN [2]; RE0001922.
RX PUBMED: 8385270.
RA Thomas H. E., Stunnenberg H. G., Stewart A. F.
RT Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle
RL Nature 362:471-475 (1993).
RN [3]; RE0003005.
RX PUBMED: 1280827.
RA Christianson A. M. K., King D. L., Hatzivassiliou E., Casas J. E., Hallenbeck P. L., Nikodem V. M., Mitsialis S. A., Kafatos F. C.
RT DNA binding and heteromerization of the Drosophila transcription factor chorion factor 1/ultraspiracle
RL Proc. Natl. Acad. Sci. USA 89:11503-11507 (1992).
RN [4]; RE0013625.
RX PUBMED: 10219237.
RA Nuclear Receptors Nomenclature Committee.
RT A unified nomenclature system for the nuclear receptor superfamily
RL Cell 97:161-163 (1999).
RN [5]; RE0013626.
RX PUBMED: 2165589.
RA Henrich V. C., Sliter T. J., Lubahn D. B., MacIntyre A., Gilbert L. I.
RT A steroid/thyroid hormone receptor superfamily member in Drosophila melanogaster that shares extensive sequence similarity with a mammalian homologue
RL Nucleic Acids Res. 18:4143-4148 (1990).
RN [6]; RE0017372.
RX PUBMED: 1330482.
RA Oro A. E., McKeown M., Evans R. M.
RT The Drosophila retinoid X receptor homolog ultraspiracle functions in both female reproduction and eye morphogenesis
RL Development 115:449-462 (1992).
XX
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