AC T00217
XX
ID T00217
XX
DT 15.10.1992 (created); ewi.
CO Copyright (C), QIAGEN.
XX
FA EcR
XX
SY ecdysone receptor; ecdysteroid receptor; ecdysterone receptor; ECR; NR1H1.
XX
OS fruit fly, Drosophila melanogaster
OC eukaryota; animalia; metazoa; arthropoda; insecta; diptera; drosophiloidea; drosophilidae
XX
CL C0002; CC (rec).
XX
SZ 878 AA; 93.8 kDa (calc.), 80-90 kDa (SDS)
XX
SQ MKRRWSNNGGFMRLPEESSSEVTSSSNGLVLPSGVNMSPSSLDSHDYCDQDLWLCGNESG
SQ SFGGSNGHGLSQQQQSVITLAMHGCSSTLPAQTTIIPINGNANGNGGSTNGQYVPGATNL
SQ GALANGMLNGGFNGMQQQIQNGHGLINSTTPSTPTTPLHLQQNLGGAGGGGIGGMGILHH
SQ ANGTPNGLIGVVGGGGGVGLGVGGGGVGGLGMQHTPRSDSVNSISSGRDDLSPSSSLNGY
SQ SANESCDAKKSKKGPAPRVQEELCLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCC
SQ KFGRACEMDMYMRRKCQECRLKKCLAVGMRPECVVPENQCAMKRREKKAQKEKDKMTTSP
SQ SSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQ
SQ LAVIYKLIWYQDGYEQPSEEDLRRIMSQPDENESQTDVSFRHITEITILTVQLIVEFAKG
SQ LPAFTKIPQEDQITLLKACSSEVMMLRMARRYDHSSDSIFFANNRSYTRDSYKMAGMADN
SQ IEDLLHFCRQMFSMKVDNVEYALLTAIVIFSDRPGLEKAQLVEAIQSYYIDTLRIYILNR
SQ HCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLKLKNRKLPKFLEEIWDVHAIPPSVQ
SQ SHLQITQEENERLERAERMRASVGGAITAGIDCDSASTSAAAAAAQHQPQPQPQPQPSSL
SQ TQNDSQHQTQPQLQPQLPPQLQGQLQPQLQPQLQTQLQPQIQPQPQLLPVSAPVPASVTA
SQ PGSLSAVSTSSEYMGGSAAIGPITPATTSSITAAVTASSTTSAVPMGNGVGVGVGVGGNV
SQ SMYANAQTAMALMGVALHSHQEQLIGGVAVKSEHSTTA
XX
SC translated from EMBL #M74078
XX
FT 261 332 
SM00399; c4gold.
FT 261 336 
PS51030; NUCLEAR_REC_DBD_2.
FT 262 337 
PF00105; Zinc finger, C4 type (two domains).
FT 272 624 
PF00478; IMP dehydrogenase / GMP reductase domai.
FT 465 625 
SM00430; holi.
FT 468 649 
PF00104; Ligand-binding domain of nuclear hormon.
XX
FF binding of RXR-alpha heterodimer, not of USP-heterodimer, is stimulated by muristerone and 9-cis-retinoic acid;
XX
IN T00117 CF1; fruit fly, Drosophila melanogaster.
IN T01331 RXR-alpha; mouse, Mus musculus.
IN T01345 RXR-alpha; human, Homo sapiens.
IN T01359 RXR-alpha; clawed frog, Xenopus laevis.
XX
BS R03988.
BS R03319.
BS R00750.
BS R03021.
BS R03328.
XX
DR TRANSPATH: MO000024779.
DR EMBL: M74078;
DR UniProtKB: P34021;
DR FLYBASE: FBgn0000546; EcR.
XX
RN [1]; RE0000362.
RX PUBMED: 16453813.
RA Riddihough G., Pelham H. R. B.
RT An ecdysone response element in the Drosophila hsp27 promoter
RL EMBO J. 6:3729-3734 (1987).
RN [2]; RE0000729.
RX PUBMED: 1899227.
RA Cherbas L., Lee K., Cherbas P.
RT Identification of ecdysone receptor elements by analysis of the Drosophila Eip28/29 gene
RL Genes Dev. 5:120-131 (1991).
RN [3]; RE0001652.
RX PUBMED: 1904544.
RA Luo Y., Amin J., Voellmy R.
RT Ecdysterone receptor is a sequence-specific transcription factor involved in the developmental regulation of heat shock genes
RL Mol. Cell. Biol. 11:3660-3675 (1991).
RN [4]; RE0001922.
RX PUBMED: 8385270.
RA Thomas H. E., Stunnenberg H. G., Stewart A. F.
RT Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle
RL Nature 362:471-475 (1993).
RN [5]; RE0013625.
RX PUBMED: 10219237.
RA Nuclear Receptors Nomenclature Committee.
RT A unified nomenclature system for the nuclear receptor superfamily
RL Cell 97:161-163 (1999).
XX
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