AC T00814
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ID T00814
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DT 20.10.1992 (created); ewi.
DT 31.03.2009 (updated); ane.
CO Copyright (C), QIAGEN.
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FA TFEA-xbb1
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SY TFE3-S.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006798 Tfe3.
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CL C0012; bHLH-ZIP.
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SZ 411 AA; 44.1 kDa (calc.).
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SQ TSGTRRREQAAAAPFPSPAPASPAISVIGVSAGGHTLSRPPPAQVPREVLKVQTHLENPT
SQ RYHLQQARRQQVKQYLSTTLGPKLASQALTPPPGPSSAQPLPAPETAHATGPTGSAPNSP
SQ MALLTIGSSSEKELPVSGNLLDVYSSQGVATPAITVSNSCPAELPNIKREISETEAKALL
SQ KERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPEMRWNKGTILKASVDYIRKLQKE
SQ QQRSKDLESRQRSLEQANRSLQLRIQELELQAQIHGLPVPPNPGLLSLTTSSVSDSLKPE
SQ QLDIEEEGRPSTTFHVSGGPAQNAPPQQPPAPPSDALLDLHFPSDHLGDLGDPFHLGLED
SQ ILMEEEGMVGGLSGGALSPLRAASDPLLSSVSPAVSNASSRRSSFSIEEES
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SC translated from EMBL #S76673 and edited
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FT 182 238 PS50888; HLH.
FT 185 238 PF00010; Helix-loop-helix DNA-binding domain.
FT 190 243 SM00353; finulus.
FT 310 411 C-terminal trans-activation domain [3].
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FF trans-dominant negative regulator;
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IN T00814 TFEA-xbb1; mouse, Mus musculus.
IN T00810 TFEA-xbb2; mouse, Mus musculus.
IN T00812 tfeb-isoform1; human, Homo sapiens.
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MX M01034 V$EBOX_Q6_01.
MX M03890 V$TFEA_Q6.
MX M01029 V$TFE_Q6.
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BS R04253.
BS R00844.
BS R00853.
BS R00240.
BS R02252.
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DR TRANSPATH: MO000025189.
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RN [1]; RE0002659.
RX PUBMED: 1840705.
RA Roman C., Cohn L., Calame K.
RT A dominant negative form of transcription activator mTFE3 created by differential splicing
RL Science 254:94-97 (1991).
RN [2]; RE0003076.
RX PUBMED: 1732746.
RA Roman C., Matera A. G., Cooper C., Artandi S., Blain S., Ward D. C., Calame K.
RT mTFE3, an X-linked transcriptional activator containing basic helix-loop-helix and zipper domains, utilizes the zipper to stabilize both DNA binding and multimerization
RL Mol. Cell. Biol. 12:817-827 (1992).
RN [3]; RE0006694.
RX PUBMED: 7479029.
RA Artandi S. E., Merrell K., Avtiahl N., Wong K.-K., Calame K.
RT TFE3 contains two activation domains, one acidic and the other proline-rich, that synergistically activate transcription
RL Nucleic Acids Res. 23:3865-3871 (1995).
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//