AC T01009
XX
ID T01009
XX
DT 28.01.1994 (created); ewi.
DT 23.10.2014 (updated); sla.
CO Copyright (C), QIAGEN.
XX
FA RSRFC4
XX
SY Mef-2a-isoform3; RSRFC4.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G003943 MEF2A; HGNC: MEF2A.
XX
CL C0014; MADS; 5.1.1.1.1.3.
XX
SZ 497 AA; 53.6 kDa (cDNA) (calc.).
XX
SQ MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYAST
SQ DMDKVLLKYTEYNEPHESRTNSDIVEALNKKEHRGCDSPDPDTSYVLTPHTEEKYKKINE
SQ EFDNMMRNHKIAPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLTDSSML
SQ SPPQTTLHRNVSPGAPQRPPSTGNAGGMLSTTDLTVPNGAGSSPVGNGFVNSRASPNLIG
SQ ATGANSLGKVMPTKSPPPPGGGNLGMNSRKPDLRVVIPPSSKGMMPPLNTQRISSSQATQ
SQ PLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFNSPGMLSLGQVSAWQ
SQ QHHLGQAALSSLVAGGQLSQGSNLSINTNQNISIKSEPISPPRDRMTPSGFQQQQQQQQQ
SQ PPPPPQPQPQPPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNTE
SQ DRESPSVKRMRMDAWVT
XX
SC conceptually translated from EMBL/GenBank/DDBJ #X63381
XX
FT 1 60 
SM00432; MADS.
FT 1 61 
PS50066; MADS_BOX_2.
FT 9 59 
PF00319; SRF-type transcription factor (DNA-binding a.
XX
SF splice variants are MEF-2, aMEF-2, and RSRFC9 [1] [2];
SF no stable heterodimers with SRF [2];
XX
CP ubiquitous (adult) [1].
CN fetal skeletal muscle [1].
XX
FF although RSRFC4 binding sequences can act as promoter elements in transfection assays, co-transfection with RSRFC4 does not lead to additional transcriptional activation [2];
XX
IN T01012 MEF-2B1; human, Homo sapiens.
IN T01785 MEF-2B1; mouse, Mus musculus.
IN T01009 RSRFC4; human, Homo sapiens.
XX
MX M00403 V$AMEF2_Q6.
MX M00406 V$HMEF2_Q6.
MX M02024 V$MEF2A_Q6.
MX M00006 V$MEF2_01.
MX M00231 V$MEF2_02.
MX M00232 V$MEF2_03.
MX M00233 V$MEF2_04.
MX M00941 V$MEF2_Q6_01.
MX M07326 V$MEF2_Q6_02.
MX M07424 V$MEF2_Q6_03.
MX M00405 V$MMEF2_Q6.
MX M00026 V$RSRFC4_01.
MX M00407 V$RSRFC4_Q2.
XX
BS R03606.
BS R05493.
BS R05494.
BS R05495.
BS R05496.
BS R05497.
BS R05498.
BS R05499.
BS R05500.
BS R05501.
BS R05502.
BS R05503.
BS R05504.
BS R05505.
BS R05506.
BS R05507.
BS R05508.
BS R05509.
BS R05510.
BS R05511.
BS R05512.
BS R05513.
BS R05514.
BS R05515.
BS R05516.
BS R05517.
BS R05518.
BS R05519.
BS R05520.
BS R05521.
BS R05522.
BS R05523.
BS R05524.
BS R05525.
BS R05526.
BS R05527.
BS R05528.
BS R05529.
BS R05530.
BS R00248.
BS R03607.
BS R04540.
XX
DR TRANSPATH: MO000025338.
DR EMBL: X63381;
DR UniProtKB: Q02078-3;
XX
RN [1]; RE0000768.
RX PUBMED: 1516833.
RA Yu Y.-T., Breitbart R. E., Smoot L. B., Lee Y., Mahdavi V., Nadal-Ginard B.
RT Human myocyte-specific enhancer factor 2 comprises a group of tissue-restricted MADS box transcription factors
RL Genes Dev. 6:1783-1798 (1992).
RN [2]; RE0000769.
RX PUBMED: 1748287.
RA Pollock R., Treisman R.
RT Human SRF-related proteins: DNA-binding properties and potential regulatory targets
RL Genes Dev. 5:2327-2341 (1991).
XX
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