AC T01012
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ID T01012
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DT 31.01.1994 (created); ewi.
DT 19.11.2007 (updated); djp.
CO Copyright (C), QIAGEN.
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FA MEF-2B1
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SY MEF-2B; MEF-2B-1; RSRFR2; xMEF-2; xMEF2.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G116926 MEF2B; HGNC: MEF2B.
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CL C0014; MADS; 5.1.1.1.2.
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SF xMEF-2 and RSRFR2 are identical, but arise from differentially spliced transcripts that differ in their 5'-UTR [1] [2];
SF its DNA-binding capability to MEF-2-sites is inhibited by C-terminal sequences [2];
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CP ubiquitous, particular high levels in B cells [2]; skeletal muscle, brain, placenta, (lung) [1] [1] [2].
CN liver, kidney [1].
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FF presumably by heterodimerization with a DNA-binding component, xMEF-2 can act as a potent transcriptional activator [1];
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IN T01012 MEF-2B1; human, Homo sapiens.
IN T01785 MEF-2B1; mouse, Mus musculus.
IN T01009 RSRFC4; human, Homo sapiens.
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MX M07424 V$MEF2_Q6_03.
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BS R09147.
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DR TRANSPATH: MO000025340.
DR UniProtKB: Q02080;
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RN [1]; RE0000768.
RX PUBMED: 1516833.
RA Yu Y.-T., Breitbart R. E., Smoot L. B., Lee Y., Mahdavi V., Nadal-Ginard B.
RT Human myocyte-specific enhancer factor 2 comprises a group of tissue-restricted MADS box transcription factors
RL Genes Dev. 6:1783-1798 (1992).
RN [2]; RE0000769.
RX PUBMED: 1748287.
RA Pollock R., Treisman R.
RT Human SRF-related proteins: DNA-binding properties and potential regulatory targets
RL Genes Dev. 5:2327-2341 (1991).
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