AC T01072
XX
ID T01072
XX
DT 24.02.1994 (created); ewi.
DT 22.02.2016 (updated); mkl.
CO Copyright (C), QIAGEN.
XX
FA TEF
XX
SY TEF; thyrotroph embryonic factor.
XX
OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G014473 Tef.
XX
HO VBP.
XX
CL C0008; bZIP.
XX
SZ 261 AA; 29.2 kDa (cDNA) (calc.), 45 kDa (SDS) [3]
XX
SQ MENPPRETRLDKEKGKEKLEEDESAAASTMAVSASLMPPIWDKTIPYDGESFHLEYMDLD
SQ EFLLENGIPASPTHLAQNLLLPVAELEGKESASSSTASPPSSSTAIFQPSETVSSTESSL
SQ EKERETPSPIDPNCVEVDVNFNPDPADLVLSSVPGGELFNPRKHKFAEEDLKPQPMIKKA
SQ KKVFVPDEQKDEKYWTRRKKNNVAAKRSRDARRLKENQITIRAAFLEKENTALRTEVAEL
SQ RKEVGKCKTIVSKYETKYGPL
XX
SC translated from EMBL #S58745
XX
FT 189 253 
SM00338; brlzneu.
FT 190 243 
PF07716; Basic region leucine zipper.
FT 191 254 
PS50217; BZIP.
XX
CP embryonic anterior pituitary; adult hippocampus, ventromedial nucleus of hypothalamus, piriform cortex, medial nucleus of the amygdala; 3 week: brain, heart, spleen; 21 week: lung, kidney, muscle, liver, heart, spleen, brain.
XX
FF activator in the developing thyrotroph [2];
FF expression varies with circadian rhythm exhibiting maximum levels in the evening and minimum levels in the morning similarly to DBP [3];
XX
IN T00183 DBP; rat, Rattus norvegicus.
IN T04875 DBP; human, Homo sapiens.
IN T01071 Hlf; human, Homo sapiens.
IN T01072 TEF; rat, Rattus norvegicus.
XX
MX M00672 V$TEF_Q6.
MX M00228 V$VBP_01.
XX
BS R03919.
BS R03920.
BS R03921.
BS R00616.
BS R03922.
BS R04273.
XX
DR TRANSPATH: MO000013484.
DR EMBL: S58745;
DR UniProtKB: P41224;
XX
RN [1]; RE0000774.
RX PUBMED: 1516826.
RA Hunger S. P., Ohyashiki K., Toyama K., Cleary M. L.
RT Hlf, a novel hepatic bZIP protein, shows altered DNA-binding properties following fusion to E2A in t(17;19) acute lymphoblastic leukemia
RL Genes Dev. 6:1608-1620 (1992).
RN [2]; RE0000788.
RX PUBMED: 1916262.
RA Drolet D. W., Scully K. M., Simmons D. M., Wegner M., Chu K., Swanson L. W., Rosenfeld M. G.
RT TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins
RL Genes Dev. 5:1739-1753 (1991).
RN [3]; RE0006598.
RX PUBMED: 8617210.
RA Fonjallaz P., Ossipow V., Wanner G., Schibler U.
RT The two PAR leucine zipper proteins, TEF and DBP, display similar circadian and tissue-specific expression, but have different target promoter preferences
RL EMBO J. 15:351-362 (1996).
XX
//