AC T01408
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ID T01408
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DT 11.12.1994 (created); ewi.
DT 06.07.2015 (updated); hna.
CO Copyright (C), QIAGEN.
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FA Fli-1
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SY Erg-B; EWSR2; Fli-1; FLI1; Friend leukemia integration 1; SIC-1; Sic1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G009821 Fli1.
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CL C0016; ETS; 3.5.2.1.5.
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CP adult thymus, spleen, lung; low in heart [2].
CN brain, kidney, muscle, testis [2].
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FF activated by proviral integration of F-MuLV in 75% of leukemic cell clones [2];
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IN T06598 AML-1; mouse, Mus musculus.
IN T00305 GATA-1; mouse, Mus musculus.
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MX M08881 V$ETSLIKE_Q4.
MX M00771 V$ETS_Q4.
MX M00971 V$ETS_Q6.
MX M02038 V$FLI1_01.
MX M07382 V$FLI1_Q5.
MX M01208 V$FLI1_Q6.
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BS R02386.
BS R04070.
BS R68658.
BS R01711.
BS R66236.
BS R66238.
BS R66239.
BS R63260.
BS R63261.
BS R26372.
BS R26373.
BS R64496.
BS R16697.
BS R14426.
BS R40594.
BS R01155.
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DR TRANSPATH: MO000046044.
DR UniProtKB: P26323; FLI1_MOUSE.
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RN [1]; RE0000282.
RX PUBMED: 8168137.
RA Golub T. R., Barker G. F., Lovett M., Gilliland D. G.
RT Fusion of PDGf receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation
RL Cell 77:307-316 (1994).
RN [2]; RE0000803.
RX PUBMED: 2044959.
RA Ben-David Y., Giddens E. B., Letwin K., Bernstein A.
RT Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1
RL Genes Dev. 5:908-918 (1991).
RN [3]; RE0002249.
RX PUBMED: 8502483.
RA Zhang L., Lemarchandel V., Romeo P.-H., Ben-David Y., Greer P., Bernstein A.
RT The Fli-1 proto-oncogene, involved in erythroleukemia and Ewing`s sarcoma, encodes a transcriptional activator with DNA-binding specifities distinct from other Ets family members
RL Oncogene 8:1621-1630 (1993).
RN [4]; RE0005316.
RX PUBMED: 8223245.
RA Klaembt C.
RT The Drosophila gene pointed encodes two ETS-like proteins which are involved in the development of the midline glial cells
RL Development 117:163-176 (1993).
RN [5]; RE0045775.
RX PUBMED: 12556498.
RA Starck J., Cohet N., Gonnet C., Sarrazin S., Doubeikovskaia Z., Doubeikovski A., Verger A., Duterque-Coquillaud M., Morle F.
RT Functional cross-antagonism between transcription factors FLI-1 and EKLF
RL Mol. Cell. Biol. 23:1390-402 (2003).
RN [6]; RE0049116.
RX PUBMED: 12379474.
RA Sarrazin S., Bonod-Bidaud C., Remy P., Mehlen P., Morle F.
RT Caspase cleavage of the transcription factor FLI-1 during preB leukemic cell death.
RL Biochim. Biophys. Acta 1592:123-127 (2002).
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