TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T01408 XX ID T01408 XX DT 11.12.1994 (created); ewi. DT 06.07.2015 (updated); hna. CO Copyright (C), QIAGEN. XX FA Fli-1 XX SY Erg-B; EWSR2; Fli-1; FLI1; Friend leukemia integration 1; SIC-1; Sic1. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G009821 Fli1. XX CL C0016; ETS; XX CP adult thymus, spleen, lung; low in heart [2]. CN brain, kidney, muscle, testis [2]. XX FF activated by proviral integration of F-MuLV in 75% of leukemic cell clones [2]; XX IN T06598 AML-1; mouse, Mus musculus. IN T00305 GATA-1; mouse, Mus musculus. XX MX M08881 V$ETSLIKE_Q4. MX M00771 V$ETS_Q4. MX M00971 V$ETS_Q6. MX M02038 V$FLI1_01. MX M07382 V$FLI1_Q5. MX M01208 V$FLI1_Q6. XX BS R02386. BS R04070. BS R68658. BS R01711. BS R66236. BS R66238. BS R66239. BS R63260. BS R63261. BS R26372. BS R26373. BS R64496. BS R16697. BS R14426. BS R40594. BS R01155. XX DR TRANSPATH: MO000046044. DR UniProtKB: P26323; FLI1_MOUSE. XX RN [1]; RE0000282. RX PUBMED: 8168137. RA Golub T. R., Barker G. F., Lovett M., Gilliland D. G. RT Fusion of PDGf receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation RL Cell 77:307-316 (1994). RN [2]; RE0000803. RX PUBMED: 2044959. RA Ben-David Y., Giddens E. B., Letwin K., Bernstein A. RT Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1 RL Genes Dev. 5:908-918 (1991). RN [3]; RE0002249. RX PUBMED: 8502483. RA Zhang L., Lemarchandel V., Romeo P.-H., Ben-David Y., Greer P., Bernstein A. RT The Fli-1 proto-oncogene, involved in erythroleukemia and Ewing`s sarcoma, encodes a transcriptional activator with DNA-binding specifities distinct from other Ets family members RL Oncogene 8:1621-1630 (1993). RN [4]; RE0005316. RX PUBMED: 8223245. RA Klaembt C. RT The Drosophila gene pointed encodes two ETS-like proteins which are involved in the development of the midline glial cells RL Development 117:163-176 (1993). RN [5]; RE0045775. RX PUBMED: 12556498. RA Starck J., Cohet N., Gonnet C., Sarrazin S., Doubeikovskaia Z., Doubeikovski A., Verger A., Duterque-Coquillaud M., Morle F. RT Functional cross-antagonism between transcription factors FLI-1 and EKLF RL Mol. Cell. Biol. 23:1390-402 (2003). RN [6]; RE0049116. RX PUBMED: 12379474. RA Sarrazin S., Bonod-Bidaud C., Remy P., Mehlen P., Morle F. RT Caspase cleavage of the transcription factor FLI-1 during preB leukemic cell death. RL Biochim. Biophys. Acta 1592:123-127 (2002). XX //