AC T01452
XX
ID T01452
XX
DT 20.04.1995 (created); ewi.
DT 28.08.2007 (updated); apk.
CO Copyright (C), QIAGEN.
XX
FA v-Fos
XX
OS FBJ MuLV, FBJ murine osteosarcoma virus
OC viridae; ss-RNA enveloped viruses; positive strand RNA viruses; retroviridae; oncovirinae; type C oncovirus group; mammalian type C oncoviruses
XX
CL C0008; bZIP.
XX
SZ 381 AA; 41.6 kDa (gene) (calc.).
XX
SQ MMFSGFNADYEASSFRCSSASPAGDSLSYYHSPADSFSSMGSPVNTQDFCADLSVSSANF
SQ IPTVTATSTSPDLQWLVQPTLVSSVAPSQTRAPHPYGLPTQSAGAYARAEMVKTVSGGRA
SQ QSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDKKSALQ
SQ TEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEASTPESEEAFT
SQ LPLLNDPEPKPSLEPVKSISNVELKAEPFDDFLFPASSRPSGSETSRSVPNVDLSGSFYA
SQ ADWEPLHSNSLGMGPMVTELEPLCTPVVTCTPLLRLPELTHAAGPVSSQRRQGSRHPDVP
SQ LPELVHYREEKHVFPQRFPST
XX
SC Swiss-Prot#P01102
XX
FT 60 84 
N-terminal transcription activation domain (N-TA) [6].
FT 135 199 
PF00170; bZIP transcription factor.
FT 135 199 
SM00338; brlzneu.
FT 137 200 
PS50217; BZIP.
XX
SF the FBJ genome gives rise to a p55 v-Fos protein (in contrast to FBR) [1];
XX
FF nuclear translocation appears not to be controlled by external signals (in contrast to c-Fos) [5];
FF v-Fos does not trans-repress expression of c-fos [4];
XX
IN T01436 MafF; chick, Gallus gallus.
IN T01437 MafG; chick, Gallus gallus.
IN T01434 MafK; chick, Gallus gallus.
XX
DR TRANSPATH: MO000025675.
DR EMBL: V01184;
DR UniProtKB: P01102;
XX
RN [1]; RE0004798.
RX PUBMED: 6283132.
RA Curran T., Teich N. M.
RT Candidate product of the FBJ murine osteosarcoma virus oncogene: characterization of a 55,000-Dalton phosphoprotein
RL J. Virol. 42:114-122 (1982).
RN [2]; RE0004799.
RX PUBMED: 6292525.
RA Curran T., Peters G., van Beveren C., Teich N. M., Verma I. M.
RT FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA
RL J. Virol. 44:674-682 (1982).
RN [3]; RE0004801.
RX PUBMED: 6383726.
RA Mueller R., Verma I. M.
RT Expression of cellular oncogenes
RL Curr. Top. Microbiol. Immunol. 112:73-115 (1984).
RN [4]; RE0004803.
RX PUBMED: 2513130.
RA Lucibello F. C., Lowag C., Neuberg M., Mueller R.
RT Trans-repression of the mouse c-fos promoter: A novel mechanism of fos-mediated trans-regulation
RL Cell 59:999-1007 (1989).
RN [5]; RE0004830.
RX PUBMED: 2119889.
RA Roux P., Blanchard J.-M., Fernandez A., Lamb N., Jeanteur P., Piechaczyk M.
RT Nuclear localization of c-Fos, but not v-Fos proteins, is controlled by extracellular signals
RL Cell 63:341-351 (1990).
RN [6]; RE0004887.
RX PUBMED: 8137828.
RA Jooss K. U., Funk M., Mueller R.
RT An autonomous N-terminal transactivation domain in Fos protein plays a crucial role in transformation
RL EMBO J. 13:1467-1475 (1994).
XX
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