AC T01436
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ID T01436
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DT 10.04.1995 (created); ewi.
DT 17.08.2006 (updated); din.
CO Copyright (C), QIAGEN.
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FA MafF
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SY Maff.
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OS chick, Gallus gallus
OC eukaryota; animalia; metazoa; chordata; vertebrata; aves; neornithes; neognathae; galliformes; phasianidae
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GE G037195 MAFF.
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CL C0008; bZIP; 1.1.3.2.1.
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SF possible ubiquitous component of NF-E2 [3];
SF in contrast to v-Maf, MafF does not dimerize with v-Jun [1];
SF binds to TRE-type MAREs (Maf recognition elements), either alone or as heterodimer with NF-E2 p45 [3];
SF enhances DNA-binding by NF-E2 p45 at least 8-fold [3];
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CP brain, heart, mesenterium, ovary.
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FF homodimer: transcriptional repressor;
FF repressing activity overcome by NF-E2 p45 [3];
FF does not transform chicken embryonic fibroblasts [2];
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IN T01436 MafF; chick, Gallus gallus.
IN T01437 MafG; chick, Gallus gallus.
IN T01434 MafK; chick, Gallus gallus.
IN T01435 MafK; mouse, Mus musculus.
IN T01441 NF-E2 p45; mouse, Mus musculus.
IN T01440 NF-E2p45; human, Homo sapiens.
IN T01598 Nrf2; chick, Gallus gallus.
IN T00888 v-Fos; FBR MuLV, FBR murine osteosarcoma virus.
IN T01452 v-Fos; FBJ MuLV, FBJ murine osteosarcoma virus.
IN T01453 v-Fos; NK24, avian retrovirus.
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MX M00983 V$MAF_Q6_01.
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DR TRANSPATH: MO000008875.
DR UniProtKB: Q90595;
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RN [1]; RE0003519.
RX PUBMED: 7891713.
RA Kataoka K., Igarashi K., Itoh K., Fujiwara K. T., Noda M., Yamamoto M., Nishizawa M.
RT Small Maf protein heterodimerize with Fos and may act as competetive repressor of the NF-E2 transcription factor
RL Mol. Cell. Biol. 15:2180-2190 (1995).
RN [2]; RE0003520.
RX PUBMED: 8361754.
RA Fujiwara K. T., Kataoka K., Nishizawa M.
RT Two new members of the maf oncogene family, mafK and mafF, encode nuclear b-Zip proteins lacking putative trans-activator domain
RL Oncogene 8:2371-2380 (1993).
RN [3]; RE0003522.
RX PUBMED: 8107826.
RA Igarashi K., Kataoka K., Itoh K., Hayashi N., Nishizawa M., Yamamoto M.
RT Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins
RL Nature 367:568-572 (1994).
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