AC T01434
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ID T01434
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DT 10.04.1995 (created); ewi.
DT 17.08.2006 (updated); din.
CO Copyright (C), QIAGEN.
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FA MafK
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SY MAFK; NF-E2 p18.
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OS chick, Gallus gallus
OC eukaryota; animalia; metazoa; chordata; vertebrata; aves; neornithes; neognathae; galliformes; phasianidae
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GE G037194 MAFK.
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CL C0008; bZIP; 1.1.3.2.3.
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SF lacking the N-terminal activation domain of other Maf factors [1] [2];
SF binds to TRE-type elements, either alone or as heterodimer with NF-E2 p45 [1] [3];
SF ubiquitous component of NF-E2;
SF three internal translation initiation codons give rise to shorter products [2];
SF no heterodimerization with v-Jun (in contrast to v-Maf) [1];
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CP widespread; high levels in lung, mesenterium, bursa of Fabricius [2].
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FF activator (heterodimer with NF-E2 p45);
FF homodimer: transcriptional repressor [3];
FF does not transform chicken fibroblasts [2];
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IN T01436 MafF; chick, Gallus gallus.
IN T01437 MafG; chick, Gallus gallus.
IN T01434 MafK; chick, Gallus gallus.
IN T01441 NF-E2 p45; mouse, Mus musculus.
IN T01440 NF-E2p45; human, Homo sapiens.
IN T01598 Nrf2; chick, Gallus gallus.
IN T00888 v-Fos; FBR MuLV, FBR murine osteosarcoma virus.
IN T01452 v-Fos; FBJ MuLV, FBJ murine osteosarcoma virus.
IN T01453 v-Fos; NK24, avian retrovirus.
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MX M02022 V$MAFK_Q3.
MX M07296 V$MAF_Q4.
MX M00983 V$MAF_Q6_01.
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DR TRANSPATH: MO000008878.
DR UniProtKB: Q90596;
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RN [1]; RE0003519.
RX PUBMED: 7891713.
RA Kataoka K., Igarashi K., Itoh K., Fujiwara K. T., Noda M., Yamamoto M., Nishizawa M.
RT Small Maf protein heterodimerize with Fos and may act as competetive repressor of the NF-E2 transcription factor
RL Mol. Cell. Biol. 15:2180-2190 (1995).
RN [2]; RE0003520.
RX PUBMED: 8361754.
RA Fujiwara K. T., Kataoka K., Nishizawa M.
RT Two new members of the maf oncogene family, mafK and mafF, encode nuclear b-Zip proteins lacking putative trans-activator domain
RL Oncogene 8:2371-2380 (1993).
RN [3]; RE0003522.
RX PUBMED: 8107826.
RA Igarashi K., Kataoka K., Itoh K., Hayashi N., Nishizawa M., Yamamoto M.
RT Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins
RL Nature 367:568-572 (1994).
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