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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T01598 XX ID T01598 XX DT 28.11.1995 (created); ewi. DT 12.11.2007 (updated); din. CO Copyright (C), QIAGEN. XX FA Nrf2 XX SY erythroid cell-derived protein with CNC homology; NFE2L2. XX OS chick, Gallus gallus OC eukaryota; animalia; metazoa; chordata; vertebrata; aves; neornithes; neognathae; galliformes; phasianidae XX GE G044950 NFE2L2. XX HO Cnc (D. melanogaster). XX CL C0008; bZIP; 1.1.1.2.3. XX SF highest overall similarity with Cnc; SF basic region almost identical with that of NF-E2 p45 and related factors [2]; SF has to heterodimerize with small Maf proteins to bind to NF-E2 elements [1] [2]; XX CP peripheral RBC; moderate in intestine, kidney; very low in brain, heart, liver, skeletal muscle [2]. XX FF strong transcriptional activator, stronger than NF-E2 p45 [2]; XX IN T01436 MafF; chick, Gallus gallus. IN T01437 MafG; chick, Gallus gallus. IN T01434 MafK; chick, Gallus gallus. IN T01435 MafK; mouse, Mus musculus. XX MX M07296 V$MAF_Q4. MX M00983 V$MAF_Q6_01. MX M07610 V$NRF2_Q3. MX M00821 V$NRF2_Q4. MX M07265 V$NRF2_Q4_01. MX M03835 V$NRF2_Q6. XX DR TRANSPATH: MO000025791. DR UniProtKB: Q90834; Q90834. XX RN [1]; RE0003519. RX PUBMED: 7891713. RA Kataoka K., Igarashi K., Itoh K., Fujiwara K. T., Noda M., Yamamoto M., Nishizawa M. RT Small Maf protein heterodimerize with Fos and may act as competetive repressor of the NF-E2 transcription factor RL Mol. Cell. Biol. 15:2180-2190 (1995). RN [2]; RE0003532. RX PUBMED: 7623813. RA Itoh K., Igarashi K., Hayashi N., Nishizawa M., Yamamoto M. RT Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteins RL Mol. Cell. Biol. 15:4184-4193 (1995). XX //