AC T01715
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ID T01715
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DT 07.03.1996 (created); ewi.
DT 10.02.2016 (updated); ros.
CO Copyright (C), QIAGEN.
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FA HOXA10
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SY homeo box A10; Hox-1.8; HOX1H; Hoxa-10; HOXA10; PL.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006209 Hoxa10.
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HO Abd-B (Drosophila).
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CL C0006; homeo; 3.1.1.8.5.
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SF a splice variant of 96 AA essentially consists of the homeo domain [1];
SF it uses a different 5' exon which is also found in HOXA9 [1];
SF HOXA10 prefers a TTAT rather than a TAAT binding sequence core [1];
SF binds cooperatively with Meis-1T03388 T03389 and stabilizes the DNA interaction complex [5];
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IN T03388 meis1-a; mouse, Mus musculus.
IN T03389 meis1-b; mouse, Mus musculus.
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MX M01464 V$HOXA10_01.
MX M03873 V$HOXA10_Q5.
MX M07257 V$HOXA10_Q6.
MX M07456 V$HOXA913_Q4.
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BS R66902.
BS R39691.
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DR TRANSPATH: MO000025891.
DR UniProtKB: P31310;
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RN [1]; RE0003899.
RX PUBMED: 7862151.
RA Benson G. V., Nguyen T.-H. E., Maas R. L.
RT The expression pattern of the murine Hoxa-10 gene and the sequence recognition of its homeodomain reveal specific properties of Abdominal B-like genes
RL Mol. Cell. Biol. 15:1591-1601 (1995).
RN [2]; RE0003902.
RX PUBMED: 8099712.
RA Goto J., Miyabayashi T., Wakamatsu Y., Takahashi N., Muramatsu M.
RT Organization and expression of mouse Hox3 cluster genes
RL Mol. Gen. Genet. 39:41-48 (1993).
RN [3]; RE0003903.
RX PUBMED: 8099045.
RA Haack H., Gruss P.
RT The establishment of murine Hox-1 expression domains during patterning of the limb
RL Dev. Biol. 157:410-422 (1993).
RN [4]; RE0003904.
RX PUBMED: 1683707.
RA Singh G., Kaur S., Stock J. L., Jenkins N. A., Gilbert D. J., Copeland N. G., Potter S. S.
RT Identification of 10 murine homeobox genes
RL Proc. Natl. Acad. Sci. USA 88:10706-10710 (1991).
RN [5]; RE0015480.
RX PUBMED: 9343407.
RA Shen W. F., Montgomery J. C., Rozenfeld S., Moskow J. J., Lawrence H. J., Buchberg A. M., Largman C.
RT AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins
RL Mol. Cell. Biol. 17:6448-6458 (1997).
RN [6]; RE0064941.
RX PUBMED: 15617687.
RA Williams T. M., Williams M. E., Innis J. W.
RT Range of HOX/TALE superclass associations and protein domain requirements for HOXA13:MEIS interaction.
RL Dev. Biol. 277:457-471 (2005).
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