AC T01872
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ID T01872
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DT 08.08.1996 (created); ewi.
DT 08.02.2012 (updated); yre.
CO Copyright (C), QIAGEN.
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FA Oct3-isoform2
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SY DADB-104B20.2; MGC22487; Oct-3; Oct-3B; Oct-4; OCT3; Oct4; Otf-3; OTF3; OTF4; POU class 5 homeobox 1; POU domain, class 5, transcription factor 1; POU5F1; POU5F1B.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002472 POU5F1; HGNC: POU5F1.
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CL C0007; POU; 3.1.10.5.1.2.
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SZ 265 AA; 30.1 kDa (cDNA) (calc.), 35 kDa (SDS)
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SQ MHFYRLFLGATRRFLNPEWKGEIDNWCVYVLTSLLPFKIQSQDIKALQKELEQFAKLLKQ
SQ KRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNE
SQ NLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVR
SQ VWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYS
SQ SVPFPEGEAFPPVSVTTLGSPMHSN
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SC Swiss-Prot#Q01860-2
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FT 43 117 
PF00157; Pou domain - N-terminal to homeobox domain.
FT 43 117 
SM00352; pou.
FT 133 193 
PS50071; HOMEOBOX_2.
FT 133 195 
PS50550; POU_HOMEODOMAIN.
FT 135 197 
SM00389; HOX_1.
FT 136 192 
PF00046; Homeobox domain.
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SF a splice variant is POU5F1A (Oct-3A) T00652 whereas POU5F1C (Oct-3C) T04471 is the product of a distinct gene [2];
SF compared with other POU proteins, the POUs domain is N-terminally truncated by 9 AA residues;
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FF activator [1];
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MX M03837 V$OCT3_Q6.
MX M01125 V$OCT4_01.
MX M01124 V$OCT4_02.
MX M00795 V$OCT_Q6.
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BS R02227.
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DR TRANSPATH: MO000046068.
DR EMBL: Z11899; HSOTF3BMR.
DR EMBL: Z11900; HSOTF3G.
DR UniProtKB: Q01860-2;
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RN [1]; RE0000424.
RX PUBMED: 2573524.
RA Schoeler H. R., Balling R., Hatzopoulos A. K., Suzuki N., Gruss P.
RT Octamer binding proteins confer transcriptional activity in early mouse embryogenesis
RL EMBO J. 8:2551-2557 (1989).
RN [2]; RE0004391.
RX PUBMED: 1408763.
RA Takeda J., Seino S., Bell G. I.
RT Human Oct3 gene family: cDNA sequences, alternative splicing, gene organization, chromosomal location, and expression at low levels in adult tissues
RL Nucleic Acids Res. 20:4613-4620 (1992).
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