AC T04471
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ID T04471
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DT 10.05.2001 (created); rio.
DT 20.04.2009 (updated); ach.
CO Copyright (C), QIAGEN.
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FA OTF3P1
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SY Oct-3C; OTF3C; OTF3P1; POU domain, class 5, transcription factor 1 pseudogene 1; POU5F1P1; POU5FLC8.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002473 POU5F1B; HGNC: POU5F1B.
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CL C0007; POU.
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SZ 359 AA; 38.6 kDa (gene) (calc.).
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SQ MAGHLASDFAFSPPPGGGGDGPWGAEPGWVDPLTWLSFQGPPGGPGIGPGVGPGSEVWGI
SQ PPCPPPYELCGGMAYCGPQVGVGLVPQGGLETSQPESEAGVGVESNSNGASPEPCTVPPG
SQ AVKLEKEKLEQNPEKSQDIKALQKELEQFAKLLKQKRITLGYTQADVGLILGVLFGKVFS
SQ QKTICRFEALQLSFKNICKLRPLLQKWVEEADNNENLQEICKAETLMQARKRKRTSIENR
SQ VRGNLENLFLQCPKPTLQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAA
SQ GSPFSGGPVSFPPAPGPHFGTPGYGSPHFTALYSSVPFPEGEVFPPVSVITLGSPMHSN
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SC translated from EMBL #Z11901
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FT 138 212 PF00157; Pou domain - N-terminal to homeobox domain.
FT 138 212 SM00352; pou.
FT 228 287 PS50071; HOMEOBOX_2.
FT 228 289 PS50550; POU_HOMEODOMAIN.
FT 230 291 SM00389; HOX_1.
FT 231 286 PF00046; Homeobox domain.
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SF OTF3P1 is a retroposon with 97.5% amino acid identity to POU5F1A (Oct-3A) T00652 whereas POU5F1A (Oct-3A) T00652 and POU5F1B (Oct-3B) T01872 are splice variants [1];
SF may have altered DNA binding properties because of a deletion of one amino acid in the DNA binding domain [1];
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MX M00795 V$OCT_Q6.
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DR TRANSPATH: MO000028321.
DR EMBL: Z11901;
DR UniProtKB: Q06416;
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RN [1]; RE0004391.
RX PUBMED: 1408763.
RA Takeda J., Seino S., Bell G. I.
RT Human Oct3 gene family: cDNA sequences, alternative splicing, gene organization, chromosomal location, and expression at low levels in adult tissues
RL Nucleic Acids Res. 20:4613-4620 (1992).
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