AC T02120
XX
ID T02120
XX
DT 21.05.1997 (created); hiwi.
DT 07.08.2013 (updated); mkl.
CO Copyright (C), QIAGEN.
XX
FA TAFII150
XX
SY TAF(II)150.
XX
OS fruit fly, Drosophila melanogaster
OC eukaryota; animalia; metazoa; arthropoda; insecta; diptera; drosophiloidea; drosophilidae
XX
HO TSM-1 (yeast).
XX
SZ 1213 AA; 138.5 kDa (cDNA) (calc.), 150 kDa (SDS)
XX
SQ METQPEVPEVPLRPFKLAHQVVSLTGISFERRSIIGVVELTIVPNSENLRLISLNAKQLR
SQ IYSVVLNDVCQADFTYFDPFQNICYKEPKSRALEVYSKHHLTAAQYTDPDVNNGELLIQV
SQ PPEGYSMIQEGQGLRIRIEFSLENPKCGVHFVIPPASTDEETQMNSSHMFTNCYENSSRL
SQ WFPCVDSFADPCTWRLEFTVDKNMTAVSCGELLEVIMTPDLRKKTFHYSVSTPVCAPNIA
SQ LAVGQFEIYVDPHMHEVTHFCLPGLLPLLKNTVRYLHEAFEFYEETLSTRYPFSCYKQVF
SQ VDELDTDISAYATMSIASVNLLHSIAIIDQTYISRTFMSRAVAEQFFGCFITSHHWSDTW
SQ LAKGIAEYLCGLYSRKCFGNNEYRAWVQSELARVVRYEEQYGGIILDCSQPPAPLPVSGT
SQ NQSAASSKQQEIVHYFPIKSLHTVSPKYVEAMRRKAHFVIRMLENRIGQELLIQVFNKQL
SQ ALASSAATTKIGAGLWSQLLISTNIFIKAIFTVTGKDMSVFMDQWVRTGGHAKFSLTSVF
SQ NRKRNTIELEIRQDYVNQRGIRKYNGPLMVQLQELDGTFKHTLQIESTLVKSDITCHSKS
SQ RRNKKKKIPLCTGEEVDMDLSAMDDSPVLWIRLDPEMILLRDLIIEQPDFQWQYQLRHER
SQ DVTAQFQAIQALQKYPTNATRLALTDTIESERCFYQVRCEAAHSLTKVANQMVASWSGPP
SQ AMLNIFRKFFGSFSAPHIIKLNNFSNFQLYFLQKAIPVAMAGLRTSHGICPPEVMRFLFD
SQ LFKYNENSRNHYTDAYYRAALVEALGETLTPVVSVAIHGTQITTDSLSTDAKLVLDEVTR
SQ LLNMEKHLPSYKYMVSVSCLKVIRKLQKFGHLPSLPHIYRSYAEYGIYLDLRIAAMECLV
SQ DFVKVDGRSEDLEHLITLLETDPDPAARHALAQLLIDNPPFTRESRSRLDKPNLVDRLWF
SQ SINRLPYDTKLRCDIVDLYYALYGTKRPNCLQAGENQSFYKDLMKDNNSSVGSVTGSFKK
SQ TSDSKSHLPTPTNTLDNEPQERQKPAMVTIKRTATEAFEVGDEIIKLERSEEITVLDEPV
SQ NVQAYDSETKVNALQADEEARDTHQAAKRLKNEMYAEDDNSSTMLDVGDSTRYESSHEEG
SQ KLKSGDGGLKKKKKKEKKKHKHKHKHRHSKDKDKERKDKDKRDPHISRLQAARQPLRTLS
SQ ARRTVATAIACRP
XX
SC translated from EMBL #X79243
XX
FT 11 429 
PF01433; Peptidase family M1.
FT 575 847 
PF00478; IMP dehydrogenase / GMP reductase domain.
XX
SF binds to TBP and to TAF(II)250 through its C-terminal sequences [1];
SF pI(calc.) = 8.9 [1];
XX
FF part of the TFIID complex;
FF may exhibit intrinsic DNA-binding properties [1];
FF confers promoter selectivity to TBP-TAF complexes (TFIID subcomplexes) together with TAF(II)250 in mediating additional requirements for an initiator and downstream elements [2];
XX
IN T02119 TAFII250; fruit fly, Drosophila melanogaster.
IN T02131 TAFII30beta; fruit fly, Drosophila melanogaster.
IN T00797 TBP; fruit fly, Drosophila melanogaster.
XX
DR TRANSPATH: MO000045984.
DR EMBL: X79243; DMDTAF150.
DR UniProtKB: Q24325; T150_DROME.
DR FLYBASE: FBgn0011836; Taf150.
XX
RN [1]; RE0005571.
RX PUBMED: 8178153.
RA Verrijzer C. P., Yokomori K., Chen J.-L., Tjian R.
RT Drosophila TAFII150: similarity to yeast gene TSM-1 and specific binding to core promoter DNA
RL Science 264:933-941 (1994).
RN [2]; RE0005596.
RX PUBMED: 7600579.
RA Verrijzer C. P., Chen J.-L., Yokomori K., Tjian R.
RT Binding of TAFs to Core Elements Directs Promotor Selectivity by RNA Polymerase II
RL Cell 81:1115-1125 (1995).
RN [3]; RE0005600.
RX PUBMED: 8276241.
RA Yokomori K., Chen J.-L., Zhou S., Tjian R.
RT Molecular cloning and characterization of dTAFII30alpha and dTAFII308beta: two small subunits of Drosophila TFIID
RL Genes Dev. 7:2587-2597 (1993).
XX
//