AC T02370
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ID T02370
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DT 30.03.1998 (created); ili.
DT 22.07.2011 (updated); pos.
CO Copyright (C), QIAGEN.
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FA Nab1
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SY Nab1; NGFI-A-binding protein 1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G014377 Nab1.
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SF similar to rat Nab1 T02369;
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CP adult: ubiquitous, most prominent in brain [1]; d16 embryo: widely expressed, highest levels in forebrain, thymus, salivary gland, and cartilage [1] [1].
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FF represses Egr1 (NGFI-A) and Krox-20 transcriptional activation [1];
FF interacts with the R1 domain of Egr1 [1];
FF resides in the nucleus [1];
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IN T00244 Egr-1; mouse, Mus musculus.
IN T00454 Egr-2; mouse, Mus musculus.
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DR TRANSPATH: MO000026360.
DR UniProtKB: Q61122;
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RN [1]; RE0006735.
RX PUBMED: 7624335.
RA Russo M. W., Sevetson B. R., Milbrandt J.
RT Identification of NAB1, a repressor of NGFI-A- and Krox20-mediated transcription
RL Proc. Natl. Acad. Sci. USA 92:6873-6877 (1995).
RN [2]; RE0064955.
RX PUBMED: 17299135.
RA Lawson M. A., Tsutsumi R., Zhang H., Talukdar I., Butler B. K., Santos S. J., Mellon P. L., Webster N. J.
RT Pulse sensitivity of the luteinizing hormone beta promoter is determined by a negative feedback loop Involving early growth response-1 and Ngfi-A binding protein 1 and 2.
RL Mol. Endocrinol. 21:1175-1191 (2007).
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