AC T02391
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ID T02391
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DT 08.04.1998 (created); ewi.
DT 11.12.2008 (updated); spi.
CO Copyright (C), QIAGEN.
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FA Mad3
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SY 4631412E13Rik; MAD3; Max dimerization protein 3; MXD3.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G014366 Mxd3.
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CL C0012; bHLH-ZIP; 1.2.6.7.2.
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SF avid DNA-binding as heterodimer with Max [1];
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FF repressor of c-Myc-mediated transcriptional activation and transformation [1];
FF primarily expressed in growth-arrested differentiating cells [1];
FF upregulation in differentiating CNS and epidermis is accompanied by downregulation of c-myc expression [1];
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IN T00489 Max-isoform2; human, Homo sapiens.
IN T09085 Max; Mammalia.
IN T02395 Sin3A-2; mouse, Mus musculus.
IN T02398 Sin3B; mouse, Mus musculus.
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MX M01034 V$EBOX_Q6_01.
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DR TRANSPATH: MO000026381.
DR UniProtKB: Q80US8;
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RN [1]; RE0006786.
RX PUBMED: 8521822.
RA Hurlin P. J., Queva C., Koskinen P. J., Steingrimsson E., Ayer D. E., Copeland N. G., Jenkins N. A., Eisenman R. N.
RT Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation
RL EMBO J. 14:5646-5659 (1995).
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